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Maria Teresa Del Vecchio

Explore the profile of Maria Teresa Del Vecchio including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 619
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Recent Articles
11.
Correale P, Marra M, Remondo C, Migali C, Misso G, Arcuri F, et al.
Eur J Cancer . 2010 Apr; 46(9):1703-11. PMID: 20399639
Cetuximab is a human-murine chimeric IgG1 monoclonal antibody to epidermal growth factor-receptor (EGFR) which exerts synergistic antitumour interactions with several cytotoxic drugs. Therefore, it is presently recommended in combination with...
12.
Correale P, Rotundo M, Del Vecchio M, Remondo C, Migali C, Ginanneschi C, et al.
J Immunother . 2010 Apr; 33(4):435-41. PMID: 20386463
Antitumor immune response and chemotherapy-induced immunomodulation in colon cancer patients represented the rationale to design new strategies, like GOLFIG chemoimmunotherapy (gemcitabine, oxaliplatin, 5-fluorouracil/folinic acid, granulocyte macrophage colony-stimulating factor, and aldesleukine),...
13.
Correale P, Tagliaferri P, Fioravanti A, Del Vecchio M, Remondo C, Montagnani F, et al.
Clin Cancer Res . 2008 Jul; 14(13):4192-9. PMID: 18593999
Purpose: GOLFIG chemoimmunotherapy regimen proved to be a safe and very active chemoimmunotherapy regimen in advanced colon cancer patients. We have thus investigated the immunobiological feedback to the treatment and...
14.
Correale P, Del Vecchio M, La Placa M, Montagnani F, Di Genova G, Gori Savellini G, et al.
J Immunother . 2008 May; 31(2):132-47. PMID: 18481383
The effects of anticancer chemotherapy on antigen-specific cytotoxic T lymphocytes (CTLs) are mostly unknown. We tested the effects of cytotoxic drugs such as 5-fluorouracil, gemcitabine, and oxaliplatin on the functional...
15.
Guarnieri A, Tirone A, Del Vecchio M, Vuolo G, Verre L, Savelli V, et al.
Ann Ital Chir . 2008 Mar; 78(5):451-2. PMID: 18338557
Urachus' carcinoma represents a rare oncologic disease with an unfavourable prognosis due to the usual delay of correct diagnosis for its anatomical localization. Its surgical treatment varies from radical cystectomy...
16.
Correale P, Del Vecchio M, Renieri T, Di Genova G, La Placa M, Remondo C, et al.
Cancer Lett . 2008 Feb; 263(2):291-301. PMID: 18291576
Background: C-IRIV/PTR-4 is a novel anticancer vaccine construct composed of immune-reconstituted influenza virosomes (IRIV) assembled with the PTH-rP derived peptide (PTR)-4, a synthetic CTL epitope with HLA-A(*)02.01 amino acid binding...
17.
Correale P, Cusi M, Micheli L, Nencini C, Del Vecchio M, Torino F, et al.
Invest New Drugs . 2006 Feb; 24(2):99-110. PMID: 16502353
Advanced colorectal cancer is a common disease with an high mortality rate. For four decades, pharmacological treatment of the advanced disease was based on the use of 5-fluorouracil alone or...
18.
Correale P, Del Vecchio M, Di Genova G, Gori Savellini G, La Placa M, Terrosi C, et al.
J Natl Cancer Inst . 2005 Oct; 97(19):1437-45. PMID: 16204693
Background: Thymidylate synthase (TS), a key enzyme in DNA synthesis, is often overexpressed in cancer cells. Some chemotherapeutic agents, such as 5-fluorouracil (5-FU), act by inhibiting TS expression. We evaluated...
19.
Correale P, Cusi M, Tsang K, Del Vecchio M, Marsili S, La Placa M, et al.
J Clin Oncol . 2005 Aug; 23(35):8950-8. PMID: 16061910
Purpose: Tumor cell killing by anticancer drugs may be supported by their immuno- and pharmacologic effects. Chemotherapy is in fact able to (A) upregulate tumor-associated antigen expression, including carcinoembryonic antigen...
20.
Correale P, Cusi M, Del Vecchio M, Aquino A, Prete S, Prete S, et al.
J Immunol . 2005 Jul; 175(2):820-8. PMID: 16002679
Gemcitabine, oxaliplatin, leucovorin, and 5-fluorouracil (GOLF) is a novel multidrug regimen inducing high levels of necrosis and apoptosis in colon carcinoma cells. This regimen is also able to promote a...