Maria Lebar
Overview
Explore the profile of Maria Lebar including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
159
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Recent Articles
1.
Maccarrone G, Lebar M, Martins-de-Souza D
Methods Mol Biol
. 2014 May;
1156:175-85.
PMID: 24791988
Proteomics has been revolutionized by the rapid advance of mass spectrometric instrumentations and techniques. Parallel methodologies for the quantification of proteomes also evolved, including in vitro stable isotope labeling. Here,...
2.
Miller I, Raposo G, Welsch U, Prazeres da Costa O, Thiel U, Lebar M, et al.
Biol Cell
. 2013 Mar;
105(7):289-303.
PMID: 23521563
Background Information: Exosomes are small RNA- and protein-containing extracellular vesicles (EVs) that are thought to mediate hetero- and homotypic intercellular communication between normal and malignant cells.Tumour-derived exosomes are believed to...
3.
Maccarrone G, Rewerts C, Lebar M, Turck C, Martins-de-Souza D
Proteomics
. 2013 Jan;
13(5):893-7.
PMID: 23281267
Peripheral blood mononuclear cells (MNCs) are accessible through blood collection and represent a useful source for investigations on disease mechanisms and treatment response. Aiming to build a reference proteome database,...
4.
Webhofer C, Gormanns P, Reckow S, Lebar M, Maccarrone G, Ludwig T, et al.
J Psychiatr Res
. 2012 Dec;
47(3):289-98.
PMID: 23207114
Most of the commonly used antidepressants block monoamine reuptake transporters to enhance serotonergic or noradrenergic neurotransmission. Effects besides or downstream of monoamine reuptake inhibition are poorly understood and yet presumably...
5.
Varadarajulu J, Lebar M, Krishnamoorthy G, Habelt S, Lu J, Weinstein I, et al.
Behav Brain Res
. 2011 Feb;
220(2):305-11.
PMID: 21316396
Several reports have implicated a role for the histidine triad nucleotide-binding protein-1 (Hint1) in psychiatric disorders. We have studied the emotional behaviour of male Hint1 knockout (Hint1 KO) mice in...
6.
Martins-de-Souza D, Lebar M, Turck C
Eur Arch Psychiatry Clin Neurosci
. 2010 Nov;
261(3):217-28.
PMID: 21088845
On the basis of impaired glutamatergic transmission and the potential role of astrocytes in schizophrenia, we treated cultured astrocytes with MK-801, an NMDA-receptor antagonist, to investigate whether the resulting proteome...
7.
Martins-de-Souza D, Schmitt A, Roder R, Lebar M, Schneider-Axmann T, Falkai P, et al.
J Psychiatr Res
. 2010 Apr;
44(14):989-91.
PMID: 20381070
Molecular knowledge about schizophrenia--a psychotic, multifactorial mental disorder that affects about 1% of the population worldwide--is limited and no diagnostic biomarkers are available. The comparative proteome analysis of human brain...
8.
Turck C, Maccarrone G, Sayan-Ayata E, Jacob A, Ditzen C, Kronsbein H, et al.
J Med Invest
. 2005 Dec;
52 Suppl:231-5.
PMID: 16366504
The identification of disease markers in tissues and body fluids requires an extensive and thorough analysis of its protein constituents. In our efforts to identify biomarkers for affective and neurological...