Maria L Toribio
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Explore the profile of Maria L Toribio including associated specialties, affiliations and a list of published articles.
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43
Citations
1212
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Recent Articles
31.
Puig-Kroger A, Aguilera-Montilla N, Martinez-Nunez R, Dominguez-Soto A, Sanchez-Cabo F, Martin-Gayo E, et al.
Immunobiology
. 2010 Jul;
215(9-10):812-20.
PMID: 20615577
RUNX proteins are heterodimeric factors that play crucial roles during development and differentiation of cells of the immune system. The RUNX3 transcription factor controls lineage decisions during thymopoiesis and T-cell...
32.
Martin-Gayo E, Sierra-Filardi E, Corbi A, Toribio M
Blood
. 2010 Apr;
115(26):5366-75.
PMID: 20357241
The generation of natural regulatory T cells (nTregs) is crucial for the establishment of immunologic self-tolerance and the prevention of autoimmunity. Still, the origin of nTregs and the mechanisms governing...
33.
Van Vlierberghe P, Palomero T, Khiabanian H, Van der Meulen J, Castillo M, Van Roy N, et al.
Nat Genet
. 2010 Mar;
42(4):338-42.
PMID: 20228800
Tumor suppressor genes on the X chromosome may skew the gender distribution of specific types of cancer. T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with an increased...
34.
Gonzalez-Garcia S, Garcia-Peydro M, Martin-Gayo E, Ballestar E, Esteller M, Bornstein R, et al.
J Exp Med
. 2009 Apr;
206(4):779-91.
PMID: 19349467
Notch1 activation is essential for T-lineage specification of lymphomyeloid progenitors seeding the thymus. Progression along the T cell lineage further requires cooperative signaling provided by the interleukin 7 receptor (IL-7R),...
35.
Identification of CMS as a cytosolic adaptor of the human pTalpha chain involved in pre-TCR function
Navarro M, Nusspaumer G, Fuentes P, Gonzalez-Garcia S, Alcain J, Toribio M
Blood
. 2007 Sep;
110(13):4331-40.
PMID: 17823309
The T-cell receptor beta (TCRbeta)/pre-TCRalpha (pTalpha) pre-TCR complex (pre-TCR) signals the expansion and differentiation of de-veloping thymocytes. Functional pro-perties of the pre-TCR rely on its unique pTalpha chain, which suggests...
36.
Dominguez-Soto A, Aragoneses-Fenoll L, Martin-Gayo E, Martinez-Prats L, Colmenares M, Naranjo-Gomez M, et al.
Blood
. 2007 Mar;
109(12):5337-45.
PMID: 17339424
Liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin [CLEC4G]) is a C-type lectin encoded within the liver/lymph node-specific intercellular adhesion molecule-3-grabbing nonintegrin (L-SIGN)/dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin...
37.
Garcia-Peydro M, de Yebenes V, Toribio M
J Immunol
. 2006 Sep;
177(6):3711-20.
PMID: 16951331
Notch signaling is critical for T cell development of multipotent hemopoietic progenitors. Yet, how Notch regulates T cell fate specification during early thymopoiesis remains unclear. In this study, we have...
38.
Zapata D, Schamel W, Torres P, Alarcon B, Rossi N, Navarro M, et al.
J Biol Chem
. 2004 Apr;
279(23):24485-92.
PMID: 15060077
We have reported the existence of biochemical and conformational differences in the alphabeta T cell receptor (TCR) complex between CD4(+) and CD8(+) CD3gamma-deficient (gamma(-)) mature T cells. In the present...
39.
Garcia-Peydro M, de Yebenes V, Toribio M
Blood
. 2003 Jun;
102(7):2444-51.
PMID: 12829602
Notch1 activity is essential for the specification of T-lineage fate in hematopoietic progenitors. Once the T-cell lineage is specified, T-cell precursors in the thymus must choose between alphabeta and gammadelta...
40.
Klein F, Feldhahn N, Lee S, Wang H, Ciuffi F, von Elstermann M, et al.
Proc Natl Acad Sci U S A
. 2003 May;
100(11):6747-52.
PMID: 12738882
The unique role of the thymus in the development of T cells was established >4 decades ago. To elucidate how uncommitted lymphoid progenitor cells are instructed to migrate from bone...