Maria L Toribio
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Explore the profile of Maria L Toribio including associated specialties, affiliations and a list of published articles.
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43
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1212
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Recent Articles
1.
H-Alcantara A, Kourani O, Marcos-Jimenez A, Martinez-Nunez P, Herranz-Martin E, Fuentes P, et al.
Cell Death Dis
. 2024 Jul;
15(7):534.
PMID: 39068166
Lymphoid tumor patients often exhibit resistance to standard therapies or experience relapse post-remission. Relapse is driven by Tumor Initiating Cells (TICs), a subset of tumor cells capable of regrowing the...
2.
Materna M, Delmonte O, Bosticardo M, Momenilandi M, Conrey P, Charmeteau-De Muylder B, et al.
Science
. 2024 Feb;
383(6686):eadh4059.
PMID: 38422122
We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts at birth persisted over time, with normal memory...
3.
Jimenez-Reinoso A, Tirado N, Martinez-Moreno A, Diaz V, Garcia-Peydro M, Hangiu O, et al.
J Immunother Cancer
. 2022 Dec;
10(12).
PMID: 36564128
Background: The dismal clinical outcome of relapsed/refractory (R/R) T cell acute lymphoblastic leukemia (T-ALL) highlights the need for innovative targeted therapies. Although chimeric antigen receptor (CAR)-engineered T cells have revolutionized...
4.
Santamaria S, Delgado M, Botas M, Castellano E, Corraliza-Gorjon I, Lafuente P, et al.
Front Immunol
. 2022 Aug;
13:825635.
PMID: 35967322
Relapsed or refractory T acute lymphoblastic leukemia (T-ALL) still carries poor prognosis. Aiming to improve outcomes, the therapeutic potential of an anti-CCR9 monoclonal antibody (mAb 92R), targeting the human chemokine-receptor...
5.
Garcia-Leon M, Mosquera M, Cela C, Alcain J, Zuklys S, Hollander G, et al.
Front Immunol
. 2022 Jun;
13:867302.
PMID: 35707539
Notch signaling is crucial for fate specification and maturation of thymus-seeding progenitors along the T-cell lineage. Recent studies have extended the role of Notch signaling to thymic epithelial cells (TECs),...
6.
Sevilla-Movilla S, Fuentes P, Rodriguez-Garcia Y, Arellano-Sanchez N, Krenn P, de Val S, et al.
Eur J Immunol
. 2022 May;
52(8):1228-1242.
PMID: 35491946
ICAP-1 regulates β1-integrin activation and cell adhesion. Here, we used ICAP-1-null mice to study ICAP-1 potential involvement during immune cell development and function. Integrin α4β1-dependent adhesion was comparable between ICAP-1-null...
7.
Blanco B, Ramirez-Fernandez A, Bueno C, Argemi-Muntadas L, Fuentes P, Aguilar-Sopena O, et al.
Cancer Immunol Res
. 2022 Apr;
10(4):498-511.
PMID: 35362043
Chimeric antigen receptor (CAR)-modified T cells have revolutionized the treatment of CD19-positive hematologic malignancies. Although anti-CD19 CAR-engineered autologous T cells can induce remission in patients with B-cell acute lymphoblastic leukemia,...
8.
Stamatakis K, Torres-Gerica P, Jimenez-Segovia A, Ramos-Munoz E, Crespo-Toro L, Fuentes P, et al.
Front Pharmacol
. 2022 Feb;
12:806395.
PMID: 35153760
Cyclooxygenase 2 (COX2) has been implicated in cancer development and metastasis. We have identified several COX2-regulated inflammation-related genes in human colorectal cancer cells and shown that some of them play...
9.
Garcillan B, Fuentes P, Marin A, Megino R, Chacon-Arguedas D, Mazariegos M, et al.
Front Cell Dev Biol
. 2021 Jul;
9:608490.
PMID: 34249896
The human αβ T-cell receptor (TCR) is composed of a variable heterodimer (TCRαβ) and three invariant dimers (CD3γε, CD3δε, and ζζ/CD247). The role of each invariant chain in the stepwise...
10.
Nguyen T, Nokin M, Teres S, Tome M, Bodineau C, Galmar O, et al.
Mol Oncol
. 2020 Dec;
15(5):1412-1431.
PMID: 33314742
The cellular receptor Notch1 is a central regulator of T-cell development, and as a consequence, Notch1 pathway appears upregulated in > 65% of the cases of T-cell acute lymphoblastic leukemia...