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Maria Grandoch

Explore the profile of Maria Grandoch including associated specialties, affiliations and a list of published articles. Areas
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Articles 68
Citations 1287
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Recent Articles
1.
Polizio A, Marino L, Rolauer L, Doviak H, Grandoch M, Toldo S, et al.
Hypertension . 2025 Feb; 82(3):e28-e30. PMID: 39970249
No abstract available.
2.
Lang A, Oehler D, Benkhoff M, Reinders Y, Barcik M, Shahrjerdi K, et al.
Biomedicines . 2024 Oct; 12(10). PMID: 39457679
Background/objectives: Acute myocardial infarction (AMI), characterized by irreversible heart muscle damage and impaired cardiac function caused by myocardial ischemia, is a leading cause of global mortality. The damage associated with...
3.
Duplessis A, Elster C, Becher S, Engel C, Lang A, Kaldirim M, et al.
Cells . 2024 Oct; 13(19. PMID: 39404396
Determination of infarct and scar size following myocardial infarction (MI) is commonly used to evaluate the efficacy of potential cardioprotective treatments in animal models. However, histological methods to determine morphological...
4.
Polizio A, Marino L, Min K, Yura Y, Rolauer L, Cochran J, et al.
Circ Res . 2024 Sep; 135(9):933-950. PMID: 39234670
Background: Hypertension incidence increases with age and represents one of the most prevalent risk factors for cardiovascular disease. Clonal events in the hematopoietic system resulting from somatic mutations in driver...
5.
Feige T, Bosbach A, Krott K, Mulorz J, Chatterjee M, Ortscheid J, et al.
Arterioscler Thromb Vasc Biol . 2024 Aug; 44(11):2294-2317. PMID: 39206542
Background: Platelets play an important role in cardiovascular and cerebrovascular diseases. Abdominal aortic aneurysm (AAA) is a highly lethal, atherosclerosis-related disease with characteristic features of progressive dilatation of the abdominal...
6.
Bouvain P, Ding Z, Kadir S, Kleimann P, Kluge N, Tiren Z, et al.
Nat Cardiovasc Res . 2024 Aug; 2(2):126-143. PMID: 39196054
Neutrophils play a complex role during onset of tissue injury and subsequent resolution and healing. To assess neutrophil dynamics upon cardiovascular injury, here we develop a non-invasive, background-free approach for...
7.
Mann C, van Alst C, Gorressen S, Nega R, Dobrev D, Grandoch M, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2024 Apr; 397(9):7201-7212. PMID: 38652279
Trained immunity of monocytes, endothelial, and smooth muscle cells augments the cytokine response to secondary stimuli. Immune training is characterized by stabilization of hypoxia-inducible factor (HIF)-1α, mTOR activation, and aerobic...
8.
Kleeschulte S, Fischinger V, Ohlke L, Bode J, Kamler M, Dobrev D, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2024 Apr; 397(9):7187-7200. PMID: 38652276
Thrombin inhibition suppresses adiposity, WAT inflammation and metabolic dysfunction in mice. Protease-activated receptor (PAR)1 does not account for thrombin-driven obesity, so we explored the culprit role of PAR4 in this...
9.
Kleimann P, Irschfeld L, Grandoch M, Flogel U, Temme S
Int J Mol Sci . 2024 Feb; 25(4). PMID: 38396989
Acquisition of immunological memory is an important evolutionary strategy that evolved to protect the host from repetitive challenges from infectious agents. It was believed for a long time that memory...
10.
Kielb J, Saffak S, Weber J, Baensch L, Shahjerdi K, Celik A, et al.
Pharmacol Ther . 2024 Jan; 254:108592. PMID: 38286163
Hormone therapy (HT) is important and frequently used both regarding replacement therapy (HRT) and gender affirming therapy (GAHT). While HRT has been effective in addressing symptoms related to hormone shortage,...