Maria E Ryan
Overview
Explore the profile of Maria E Ryan including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
186
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Recent Articles
1.
Gu Y, Raja V, Lee H, Hong H, Prestwich G, Ryan M
J Inflamm (Lond)
. 2021 Sep;
18(1):26.
PMID: 34481488
Background: Chronic periodontitis is associated with an increased risk for systemic conditions such as cardiovascular disease, diabetes, and osteoporosis. During chronic periodontitis, endotoxin (lipopolysaccharide, LPS) produced by P. gingivalis provokes...
2.
Gu Y, Golub L, Lee H, Hou W, Ryan M
Am J Dent
. 2021 May;
34(2):97-100.
PMID: 33940667
Purpose: This pilot study assessed the periodontal status and biomarkers of systemic inflammation in acute coronary syndrome (ACS) patients. Methods: 15 ACS patients on statin (anti-cholesterol) therapy, were recruited into...
3.
Savage J, Pulsipher A, Rao N, Kennedy T, Prestwich G, Ryan M, et al.
PLoS One
. 2016 Jun;
11(6):e0157310.
PMID: 27308827
Background: Periodontitis is characterized by microbial infection, inflammation, tissue breakdown, and accelerated loss of alveolar bone matrix. Treatment targeting these multiple stages of the disease provides ways to treat or...
4.
Lauhio A, Tervahartiala T, Leppilahti J, Golub L, Ryan M, Sorsa T
Clin Infect Dis
. 2015 Jul;
61(6):1031.
PMID: 26188207
No abstract available.
5.
Gu Y, Walker C, Ryan M, Payne J, Golub L
J Oral Microbiol
. 2012 Oct;
4.
PMID: 23071896
In 1983, it was first reported that tetracyclines (TCs) can modulate the host response, including (but not limited to) inhibition of pathologic matrix metalloproteinase (MMP) activity, and by mechanisms unrelated...
6.
Gu Y, Lee H, Sorsa T, Salminen A, Ryan M, Slepian M, et al.
Pharmacol Res
. 2011 Jul;
64(6):573-9.
PMID: 21771657
Periodontitis, one of the most common chronic inflammatory diseases afflicting man, is increasingly being recognized as a risk factor for atherosclerotic cardiovascular disease (ASCVD). Non-antimicrobial tetracyclines are known to have...
7.
Golub L, Lee H, Stoner J, Sorsa T, Reinhardt R, Wolff M, et al.
J Periodontol
. 2008 Aug;
79(8):1409-18.
PMID: 18672990
Background: We recently demonstrated that a 2-year subantimicrobial-dose doxycycline (SDD) regimen (double-masked, placebo-controlled clinical trial) in postmenopausal (PM) women exhibiting mild systemic bone loss (osteopenia) and local bone loss (periodontitis)...
8.
Novak M, Dawson 3rd D, Magnusson I, Karpinia K, Polson A, Polson A, et al.
J Periodontol
. 2008 Jan;
79(1):33-41.
PMID: 18166090
Background: Previous studies showed that host modulation therapy (HMT) or topical antimicrobial therapy (TAT) provided significant adjunctive benefits to scaling and root planing (SRP) in the treatment of chronic periodontitis...
9.
Reinhardt R, Stoner J, Golub L, Wolff M, Lee H, Lee H, et al.
J Clin Periodontol
. 2007 Aug;
34(9):768-75.
PMID: 17716312
Aims: To determine the clinical efficacy of a 2-year continuous sub-antimicrobial dose doxycycline (SDD; 20 mg bid) in post-menopausal, osteopenic, oestrogen-deficient women on periodontal maintenance. Materials And Methods: One-hundred and...
10.
Walker S, Carnu O, Tuter G, Ryan M
FEMS Immunol Med Microbiol
. 2006 Sep;
48(2):218-22.
PMID: 16995879
Streptococcus pneumoniae produces a zinc-dependent proteinase that cleaves human immunoglobulin (Ig) A1 in the hinge region. This metalloproteinase is hypothesized to act as a virulence factor by allowing S. pneumoniae...