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Marek Kochanczyk

Explore the profile of Marek Kochanczyk including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 470
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Recent Articles
1.
Nalecz-Jawecki P, Szyc P, Grabowski F, Kochanczyk M, Lipniacki T
PLoS Comput Biol . 2025 Feb; 21(2):e1012846. PMID: 39982962
Motivated by the spatiotemporal waves of MAPK/ERK activity, crucial for long-range communication in regenerating tissues, we investigated stochastic homoclinic fronts propagating through channels formed by directly interacting cells. We evaluated...
2.
Korwek Z, Czerkies M, Jaruszewicz-Blonska J, Prus W, Kosiuk I, Kochanczyk M, et al.
Sci Signal . 2023 Dec; 16(815):eabq1173. PMID: 38085817
Type I interferons (IFNs) are key coordinators of the innate immune response to viral infection, which, through activation of the transcriptional regulators STAT1 and STAT2 (STAT1/2) in bystander cells, induce...
3.
Grabowski F, Kochanczyk M, Korwek Z, Czerkies M, Prus W, Lipniacki T
PLoS Pathog . 2023 Sep; 19(9):e1011597. PMID: 37669278
When infected with a virus, cells may secrete interferons (IFNs) that prompt nearby cells to prepare for upcoming infection. Reciprocally, viral proteins often interfere with IFN synthesis and IFN-induced signaling....
4.
Nalecz-Jawecki P, Gagliardi P, Kochanczyk M, Dessauges C, Pertz O, Lipniacki T
PLoS Comput Biol . 2023 May; 19(5):e1011155. PMID: 37216347
Living cells utilize signaling pathways to sense, transduce, and process information. As the extracellular stimulation often has rich temporal characteristics which may govern dynamic cellular responses, it is important to...
5.
Czerkies M, Kochanczyk M, Korwek Z, Prus W, Lipniacki T
J Virol . 2022 Nov; 96(22):e0134122. PMID: 36326278
We observed the interference between two prevalent respiratory viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV) (H1N1), and characterized its molecular underpinnings in alveolar epithelial cells (A549). We...
6.
Grabowski F, Kochanczyk M, Lipniacki T
Viruses . 2022 Feb; 14(2). PMID: 35215887
Omicron, the novel highly mutated SARS-CoV-2 Variant of Concern (VOC, Pango lineage B.1.1.529) was first collected in early November 2021 in South Africa. By the end of November 2021, it...
7.
Grabowski F, Preibisch G, Gizinski S, Kochanczyk M, Lipniacki T
Viruses . 2021 Apr; 13(3). PMID: 33804556
The novel SARS-CoV-2 Variant of Concern (VOC)-202012/01 (also known as B.1.1.7), first collected in United Kingdom on 20 September 2020, is a rapidly growing lineage that in January 2021 constituted...
8.
Kochanczyk M, Lipniacki T
Sci Rep . 2021 Jan; 11(1):2425. PMID: 33510274
Countries worldwide have adopted various strategies to minimize the socio-economic impact of the ongoing COVID-19 pandemic. Stringency of imposed measures universally reflects the standpoint from which protecting public health and...
9.
Kochanczyk M, Grabowski F, Lipniacki T
R Soc Open Sci . 2020 Oct; 7(9):200786. PMID: 33047040
The basic reproduction number of the coronavirus disease 2019 has been estimated to range between 2 and 4. Here, we used an SEIR model that properly accounts for the distribution...
10.
Grabowski F, Czyz P, Kochanczyk M, Lipniacki T
J R Soc Interface . 2019 Mar; 16(152):20180792. PMID: 30836891
Two important signalling pathways of NF-κB and ERK transmit merely 1 bit of information about the level of extracellular stimulation. It is thus unclear how such systems can coordinate complex...