Marein A W P de Jong
Overview
Explore the profile of Marein A W P de Jong including associated specialties, affiliations and a list of published articles.
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17
Citations
892
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Recent Articles
1.
Deeks S, Archin N, Cannon P, Collins S, Jones R, de Jong M, et al.
Nat Med
. 2021 Dec;
27(12):2085-2098.
PMID: 34848888
Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong treatment is required and there is no cure. HIV can integrate in the host genome and persist...
2.
van den Berg L, Cardinaud S, van der Aar A, Sprokholt J, de Jong M, Zijlstra-Willems E, et al.
J Immunol
. 2015 Jul;
195(4):1763-73.
PMID: 26170391
Human epidermal and mucosal Langerhans cells (LCs) express the C-type lectin receptor langerin that functions as a pattern recognition receptor. LCs are among the first immune cells to interact with...
3.
Gringhuis S, Kaptein T, Wevers B, van der Vlist M, Klaver E, Van Die I, et al.
Nat Commun
. 2014 Oct;
5:5074.
PMID: 25278262
Dendritic cells (DCs) orchestrate antibody-mediated responses to combat extracellular pathogens including parasites by initiating T helper cell differentiation. Here we demonstrate that carbohydrate-specific signalling by DC-SIGN drives follicular T helper...
4.
van der Vlist M, de Witte L, de Vries R, Litjens M, de Jong M, Fluitsma D, et al.
Eur J Immunol
. 2011 Jul;
41(9):2619-31.
PMID: 21739428
Langerhans cells (LCs) are a subset of DCs that reside in the upper respiratory tract and are ideally suited to sense respiratory virus infections. Measles virus (MV) is a highly...
5.
van den Berg L, de Jong M, de Witte L, Ulrich M, Geijtenbeek T
Cell Immunol
. 2011 Feb;
268(1):29-36.
PMID: 21345420
Human skin contains epidermal Langerhans cells (LCs) and dermal dendritic cells (DCs) that are key players in induction of adaptive immunity upon infection. After major burn injury, suppressed adaptive immunity...
6.
de Jong M, Geijtenbeek T
Trends Immunol
. 2010 Oct;
31(12):452-9.
PMID: 21030306
Langerhans cells (LCs) are at the frontline in defense against mucosal infections because they line the mucosal tissues and are ideally situated to intercept pathogens. Recent data suggest that LCs...
7.
de Jong M, de Witte L, Taylor M, Geijtenbeek T
J Immunol
. 2010 Jul;
185(3):1633-41.
PMID: 20592277
Genital herpes is the most prevalent viral sexually transmitted infection worldwide and is mainly caused by HSV type 2 (HSV-2). HSV-2 infection enhances HIV-1 susceptibility, even in the absence of...
8.
de Jong M, Vriend L, Theelen B, Taylor M, Fluitsma D, Boekhout T, et al.
Mol Immunol
. 2010 Jan;
47(6):1216-25.
PMID: 20097424
Langerhans cells (LCs) lining the stratified epithelia and mucosal tissues are the first antigen presenting cells to encounter invading pathogens, such as viruses, bacteria and fungi. Fungal infections form a...
9.
de Jong M, de Witte L, Santegoets S, Fluitsma D, Taylor M, de Gruijl T, et al.
J Leukoc Biol
. 2010 Jan;
87(4):637-43.
PMID: 20042470
Sexual transmission is the primary route of HIV-1 infection, and DC subsets are thought to be involved in viral dissemination to T cells. In the genital mucosa, two main subsets...
10.
de Jong M, de Witte L, Geijtenbeek T
Methods Mol Biol
. 2009 Nov;
595:55-65.
PMID: 19941105
Langerhans cells (LCs) are the main population of antigen-presenting cells lining the epidermis and stratified mucosal epithelia (1). Therefore, they play an important role in the first line of defense...