Marco Scocchi
Overview
Explore the profile of Marco Scocchi including associated specialties, affiliations and a list of published articles.
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67
Citations
1538
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Recent Articles
1.
Di Stasi A, Bozzer S, Pacor S, de Pascale L, Morici M, Favero L, et al.
Open Biol
. 2024 Dec;
14(12):240286.
PMID: 39626774
Proline-rich antimicrobial peptides (PrAMPs) have gained attention due to their antimicrobial properties and low cytotoxicity. B7-005, a small optimized PrAMP, exhibits a broader spectrum of activity than native PrAMPs, due...
2.
Koller T, Berger M, Morici M, Paternoga H, Bulatov T, Di Stasi A, et al.
Nat Chem Biol
. 2024 Oct;
20(12):1691-1700.
PMID: 39420228
The paenilamicins are a group of hybrid nonribosomal peptide-polyketide compounds produced by the honey bee pathogen Paenibacillus larvae that display activity against Gram-positive pathogens, such as Staphylococcus aureus. While paenilamicins...
3.
Koller T, Berger M, Morici M, Paternoga H, Bulatov T, Di Stasi A, et al.
bioRxiv
. 2024 Jun;
PMID: 38826346
The paenilamicins are a group of hybrid non-ribosomal peptide-polyketide compounds produced by the honey bee pathogen that display activity against Gram-positive pathogens, such as . While paenilamicins have been shown...
4.
Biondi B, de Pascale L, Mardirossian M, Di Stasi A, Favaro M, Scocchi M, et al.
Sci Rep
. 2023 Sep;
13(1):15132.
PMID: 37704689
Cathelicidins, a family of host defence peptides in vertebrates, play an important role in the innate immune response, exhibiting antimicrobial activity against many bacteria, as well as viruses and fungi....
5.
Gambato S, Bellotto O, Mardirossian M, Di Stasi A, Gennaro R, Pacor S, et al.
Bioconjug Chem
. 2023 Jun;
34(7):1212-1220.
PMID: 37379329
Resistance to aminoglycoside antibiotics is a serious problem, typically arising from inactivating enzymes, reduced uptake, or increased efflux in the important pathogens for which they are used as treatment. Conjugating...
6.
Vida V, Minisini M, Mardirossian M, Brancolini C, Scocchi M, Forzato C, et al.
RSC Adv
. 2023 Jan;
13(1):456-463.
PMID: 36605622
Cinnamic acids are an important class of phenolic compounds, which have many beneficial effects on human health but are also interesting synthetic intermediates thanks to the presence of several reactive...
7.
Degasperi M, Sgarra R, Mardirossian M, Pacor S, Maschio M, Scocchi M
Antibiotics (Basel)
. 2022 Mar;
11(3).
PMID: 35326782
As bioactive small proteins with antimicrobial and immunomodulatory activities that are naturally produced by all living organisms, antimicrobial peptides (AMPs) have a marked potential as next-generation antibiotics. However, their development...
8.
Pompilio A, Scocchi M, Mangoni M, Shirooie S, Serio A, da Costa Y, et al.
Crit Rev Microbiol
. 2022 Mar;
49(1):117-149.
PMID: 35313120
Most human infectious diseases are caused by microorganisms growing as biofilms. These three-dimensional self-organized communities are embedded in a dense matrix allowing microorganisms to persistently inhabit abiotic and biotic surfaces...
9.
Hilpert K, Gani J, Rumancev C, Simpson N, Lopez-Perez P, Garamus V, et al.
Front Pharmacol
. 2021 Dec;
12:769739.
PMID: 34966279
Antimicrobial peptides (AMPs) are a promising class of compounds being developed against multi-drug resistant bacteria. Hybridization has been reported to increase antimicrobial activity. Here, two proline-rich peptides (consP1: VRKPPYLPRPRPRPL-CONH and...
10.
Mardirossian M, Rubini M, Adamo M, Scocchi M, Saviano M, Tossi A, et al.
Molecules
. 2021 Dec;
26(23).
PMID: 34885985
The 3D structure and surface characteristics of proteins and peptides are crucial for interactions with receptors or ligands and can be modified to some extent to modulate their biological roles...