Marcin P Mycko
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Explore the profile of Marcin P Mycko including associated specialties, affiliations and a list of published articles.
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42
Citations
2101
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Recent Articles
1.
Androdias G, Lunemann J, Maillart E, Amato M, Audoin B, Bruijstens A, et al.
Brain
. 2024 Dec;
PMID: 39707906
The development of disease-modifying therapies (DMTs) for the treatment of multiple sclerosis (MS) has been highly successful in recent decades. It is now widely accepted that early initiation of DMTs...
2.
Cichalewska-Studzinska M, Szymanski J, Stec-Martyna E, Perdas E, Studzinska M, Jerczynska H, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39518908
CD4+ T cells are considered the main orchestrators of autoimmune diseases. Their disruptive effect on CD4+ T cell differentiation and the imbalance between T helper cell populations can be most...
3.
Selmaj K, Hartung H, Mycko M, Selmaj I, Cross A
J Neurol
. 2024 Aug;
271(10):6426-6438.
PMID: 39093335
Almost all currently licensed disease-modifying therapies (DMTs) for MS treatment require prolonged if not lifelong administration. Yet, as people age, the immune system has increasingly reduced responsiveness, known as immunosenescence....
4.
Siwek T, Zwiernik B, Jezierska-Wozniak K, Jezierska K, Mycko M, Selmaj K
Front Neurol
. 2024 Feb;
15:1345503.
PMID: 38370525
Background And Objectives: X-linked adrenomyeloneuropathy (AMN) is an inherited neurodegenerative disorder associated with mutations in the ABCD1 gene and the accumulation of very long-chain fatty acids (VLFCAs) in plasma and...
5.
Carlberg C, Mycko M
Cells
. 2023 Oct;
12(19).
PMID: 37830605
Environmental triggers often work via signal transduction cascades that modulate the epigenome and transcriptome of cell types involved in the disease process. Multiple sclerosis (MS) is an autoimmune disease affecting...
6.
7.
Kalkowski L, Walczak P, Mycko M, Malysz-Cymborska I
Med Res Rev
. 2023 May;
43(6):2237-2259.
PMID: 37203228
Multiple sclerosis is a chronic demyelinating disease with different disease phenotypes. The current FDA-approved disease-modifying therapeutics (DMTs) cannot cure the disease, but only alleviate the disease progression. While the majority...
8.
Mycko M, Zurawska A, Selmaj I, Selmaj K
Front Immunol
. 2022 Jun;
13:875994.
PMID: 35720271
Circular RNA (circRNA) molecules represent a novel and unique class of endogenous non-coding RNAs controlling the expression and function of microRNA (miRNA) and post-transcriptional regulation. Recent studies implicated circRNA in...
9.
Selmaj K, Mycko M, Furlan R, Rejdak K
Curr Opin Neurol
. 2022 Jun;
35(3):286-292.
PMID: 35674070
Purpose Of Review: Multiple sclerosis (MS) is highly heterogenic disorder with respect to clinical course, diagnosis, and treatment response. There is an urgent need to search for simply and reliable...
10.
Zurawska A, Mycko M, Selmaj I, Raine C, Selmaj K
Neurol Neuroimmunol Neuroinflamm
. 2021 Aug;
8(5).
PMID: 34385287
Background And Objectives: To investigate the total circular RNA (circRNA) profile in patients with relapsing-remitting multiple sclerosis (RRMS) and healthy controls (HCs). Methods: Hybridization microarray was used to define the...