Hanna Cwiklinska
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Explore the profile of Hanna Cwiklinska including associated specialties, affiliations and a list of published articles.
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11
Citations
273
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Recent Articles
1.
Cwiklinska H, Cichalewska-Studzinska M, Selmaj K, Mycko M
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32316658
T helper cells type 17 (Th17) are orchestrators of autoimmune conditions, including multiple sclerosis (MS), but mechanisms of Th17 pathogenicity remain unknown. MicroRNAs (miRNA) are known to control T cells....
2.
miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40
Mycko M, Cichalewska M, Cwiklinska H, Selmaj K
J Neurosci
. 2015 Dec;
35(50):16504-15.
PMID: 26674874
Significance Statement: Multiple sclerosis (MS) is brain-specific autoimmune disease mediated by T helper (Th) cells autoreactive to myelin. The mechanisms leading to MS are not fully understood and microRNAs (miRNAs)...
3.
Lewkowicz P, Cwiklinska H, Mycko M, Cichalewska M, Domowicz M, Lewkowicz N, et al.
J Neurosci
. 2015 May;
35(19):7521-37.
PMID: 25972178
MicroRNAs (miRNAs) associate with Argonaute (Ago), GW182, and FXR1 proteins to form RNA-induced silencing complexes (RISCs). RISCs represent a critical checkpoint in the regulation and bioavailability of miRNAs. Recent studies...
4.
Mycko M, Sliwinska B, Cichalewska M, Cwiklinska H, Raine C, Selmaj K
J Neurosci
. 2014 Jun;
34(25):8646-58.
PMID: 24948818
The CNS is considered an immune privileged site because its repertoire of highly immunogenic molecules remains unseen by the immune system under normal conditions. However, the mechanism underlying the inhibition...
5.
Mycko M, Cwiklinska H, Cichalewska M, Matysiak M, Lewkowicz P, Sliwinska B, et al.
Clin Immunol
. 2014 May;
153(1):211-9.
PMID: 24814238
Plasmacytoid dendritic cells (pDCs), an important immunoregulatory population, are characterized by vigorous secretion of type I interferons (IFNs) in response to toll-like receptor (TLR) 7 and 9 stimulation. We studied...
6.
Jablonowska E, Wojcik K, Szymanska B, Omulecka A, Cwiklinska H, Piekarska A
PLoS One
. 2014 Apr;
9(4):e95564.
PMID: 24752012
Aim: To analyze the expression of HMOX1 and miR-122 in liver biopsy samples obtained from HCV mono-and HIV/HCV co-infected patients in relation to selected clinical parameters, histological examination and IL-28B...
7.
Mycko M, Cichalewska M, Machlanska A, Cwiklinska H, Mariasiewicz M, Selmaj K
Proc Natl Acad Sci U S A
. 2012 Apr;
109(20):E1248-57.
PMID: 22517757
MicroRNAs (miRNAs) are an emerging group of short, noncoding RNAs that play an important role in regulating expression of classical genes. Thus far little is known about their role in...
8.
Cwiklinska H, Mycko M, Szymanska B, Matysiak M, Selmaj K
J Neurosci Res
. 2010 Sep;
88(14):3102-10.
PMID: 20806409
Heat shock protein 70 (Hsp70), a prominent member of the heat shock protein family, is a stress-induced chaperone, contributing to the "protein triage" mechanism. However, we and others have previously...
9.
Mycko M, Cwiklinska H, Walczak A, Libert C, Raine C, Selmaj K
Eur J Immunol
. 2008 Jun;
38(7):1999-2013.
PMID: 18581325
Protracted inflammation has been associated with the generation of autoimmune responses. In this respect, increase in the chaperonin, heat shock protein 70 (hsp70) is an outcome of prolonged inflammatory stress....
10.
Mycko M, Cwiklinska H, Szymanski J, Szymanska B, Kudla G, Kilianek L, et al.
J Immunol
. 2003 Dec;
172(1):202-13.
PMID: 14688327
In this study, we investigated the role of the inducible form of heat shock protein 70 (hsp70) in the presentation of the major putative autoantigen in multiple sclerosis, myelin basic...