Igor Selmaj
Overview
Explore the profile of Igor Selmaj including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
214
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0
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Recent Articles
1.
Selmaj K, Hartung H, Mycko M, Selmaj I, Cross A
J Neurol
. 2024 Aug;
271(10):6426-6438.
PMID: 39093335
Almost all currently licensed disease-modifying therapies (DMTs) for MS treatment require prolonged if not lifelong administration. Yet, as people age, the immune system has increasingly reduced responsiveness, known as immunosenescence....
2.
Mycko M, Zurawska A, Selmaj I, Selmaj K
Front Immunol
. 2022 Jun;
13:875994.
PMID: 35720271
Circular RNA (circRNA) molecules represent a novel and unique class of endogenous non-coding RNAs controlling the expression and function of microRNA (miRNA) and post-transcriptional regulation. Recent studies implicated circRNA in...
3.
Zurawska A, Mycko M, Selmaj I, Raine C, Selmaj K
Neurol Neuroimmunol Neuroinflamm
. 2021 Aug;
8(5).
PMID: 34385287
Background And Objectives: To investigate the total circular RNA (circRNA) profile in patients with relapsing-remitting multiple sclerosis (RRMS) and healthy controls (HCs). Methods: Hybridization microarray was used to define the...
4.
Selmaj K, Selmaj I
Neurol Neurochir Pol
. 2019 Oct;
53(5):317-326.
PMID: 31664710
Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory demyelinating diseases of the central nervous system (CNS) that cause optic neuritis, transverse myelitis, and some other CNS syndromes. Recently, diagnosis and understanding...
5.
Selmaj I, Cichalewska M, Namiecinska M, Galazka G, Horzelski W, Selmaj K, et al.
Ann Neurol
. 2017 Apr;
81(5):703-717.
PMID: 28411393
Objective: Accumulating evidence supports a role for exosomes in immune regulation. In this study, we investigated the total circulating exosome transcriptome in relapsing-remitting multiple sclerosis (RRMS) patients and healthy controls...
6.
Selmaj I, Mycko M, Raine C, Selmaj K
J Neuroimmunol
. 2017 Apr;
306:1-10.
PMID: 28385180
Multiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS) in which autoreactive immune cells recognizing myelin antigens lead to demyelination and axonal injury. Mechanisms relevant...
7.
Galazka G, Mycko M, Selmaj I, Raine C, Selmaj K
Mult Scler
. 2017 Mar;
24(4):449-458.
PMID: 28273783
Background: Exosomes are small extracellular vesicles that provide cell-to-cell communication and are involved in immunoregulation. Objective: To investigate serum exosomes for the presence of myelin proteins outside the central nervous...
8.
Mycko M, Cwiklinska H, Cichalewska M, Matysiak M, Lewkowicz P, Sliwinska B, et al.
Clin Immunol
. 2014 May;
153(1):211-9.
PMID: 24814238
Plasmacytoid dendritic cells (pDCs), an important immunoregulatory population, are characterized by vigorous secretion of type I interferons (IFNs) in response to toll-like receptor (TLR) 7 and 9 stimulation. We studied...