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Marcelo M Samsa

Explore the profile of Marcelo M Samsa including associated specialties, affiliations and a list of published articles. Areas
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Citations 605
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Kackos C, DeBeauchamp J, Davitt C, Lonzaric J, Sealy R, Hurwitz J, et al.
NPJ Vaccines . 2023 Oct; 8(1):157. PMID: 37828126
Annually, seasonal influenza is responsible for millions of infections and hundreds of thousands of deaths. The current method for managing influenza is vaccination using a standardized amount of the influenza...
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Kackos C, Surman S, Jones B, Sealy R, Jeevan T, Davitt C, et al.
Microbiol Spectr . 2023 Jan; 11(1):e0424022. PMID: 36695597
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in December of 2019 and is responsible for millions of infections and deaths across the globe. Vaccination against...
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Samsa M, Dupuy L, Beard C, Six C, Schmaljohn C, Mason P, et al.
Mol Ther . 2019 Feb; 27(4):850-865. PMID: 30770173
Venezuelan equine encephalitis virus (VEEV) is a known biological defense threat. A live-attenuated investigational vaccine, TC-83, is available, but it has a high non-response rate and can also cause severe...
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Iglesias N, Mondotte J, Byk L, De Maio F, Samsa M, Alvarez C, et al.
Traffic . 2015 Jun; 16(9):962-77. PMID: 26031340
Dengue viruses cause the most important human viral disease transmitted by mosquitoes. In recent years, a great deal has been learned about molecular details of dengue virus genome replication; however,...
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Samsa M, Mondotte J, Caramelo J, Gamarnik A
J Virol . 2011 Nov; 86(2):1046-58. PMID: 22072762
Little is known about the mechanism of flavivirus genome encapsidation. Here, functional elements of the dengue virus (DENV) capsid (C) protein were investigated. Study of the N-terminal region of DENV...
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Samsa M, Mondotte J, Iglesias N, Assuncao-Miranda I, Barbosa-Lima G, Da Poian A, et al.
PLoS Pathog . 2009 Oct; 5(10):e1000632. PMID: 19851456
Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent...
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Filomatori C, Lodeiro M, Alvarez D, Samsa M, Pietrasanta L, Gamarnik A
Genes Dev . 2006 Aug; 20(16):2238-49. PMID: 16882970
The mechanisms of RNA replication of plus-strand RNA viruses are still unclear. Here, we identified the first promoter element for RNA synthesis described in a flavivirus. Using dengue virus as...