Marcel Tiebe
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Explore the profile of Marcel Tiebe including associated specialties, affiliations and a list of published articles.
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8
Citations
312
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Recent Articles
1.
Camilleri-Robles C, Amador R, Tiebe M, Teleman A, Serras F, Guigo R, et al.
NAR Genom Bioinform
. 2024 Aug;
6(3):lqae091.
PMID: 39157585
The discovery of functional long non-coding RNAs (lncRNAs) changed their initial concept as transcriptional noise. LncRNAs have been identified as regulators of multiple biological processes, including chromatin structure, gene expression,...
2.
Nuskova H, Cortizo F, Schwenker L, Sachsenheimer T, Diakonov E, Tiebe M, et al.
J Biol Chem
. 2023 Jul;
299(9):105088.
PMID: 37495107
S-acylation is a reversible posttranslational protein modification consisting of attachment of a fatty acid to a cysteine via a thioester bond. Research over the last few years has shown that...
3.
Tiebe M, Lutz M, Senyilmaz Tiebe D, Teleman A
Sci Rep
. 2019 Dec;
9(1):19869.
PMID: 31882710
We previously identified Drosophila REPTOR and REPTOR-BP as transcription factors downstream of mTORC1 that play an important role in regulating organismal metabolism. We study here the mammalian ortholog of REPTOR-BP,...
4.
Kwiatkowski S, Seliga A, Vertommen D, Terreri M, Ishikawa T, Grabowska I, et al.
Elife
. 2018 Dec;
7.
PMID: 30526847
Protein histidine methylation is a rare post-translational modification of unknown biochemical importance. In vertebrates, only a few methylhistidine-containing proteins have been reported, including β-actin as an essential example. The evolutionary...
5.
Tiebe M, Lutz M, Levy D, Teleman A
PLoS One
. 2018 Aug;
13(8):e0201609.
PMID: 30067821
Lysine methylation is a reversible post-translational modification that affects protein function. Lysine methylation is involved in regulating the function of both histone and non-histone proteins, thereby influencing both cellular transcription...
6.
Tiebe M, Lutz M, De La Garza A, Buechling T, Boutros M, Teleman A
Dev Cell
. 2015 Apr;
33(3):272-84.
PMID: 25920570
TORC1 regulates growth and metabolism, in part, by influencing transcriptional programs. Here, we identify REPTOR and REPTOR-BP as transcription factors downstream of TORC1 that are required for ∼ 90% of...
7.
Strassburger K, Tiebe M, Pinna F, Breuhahn K, Teleman A
Dev Biol
. 2012 May;
367(2):187-96.
PMID: 22609549
The insulin/IGF signaling (IIS) pathway is a potent inducer of cell proliferation in normal development and in cancer. The mechanism by which this occurs, however, is not completely understood. The...
8.
Hoppe S, Bierhoff H, Cado I, Weber A, Tiebe M, Grummt I, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(42):17781-6.
PMID: 19815529
AMP-activated protein kinase (AMPK) senses changes in the intracellular AMP/ATP ratio, switching off energy-consuming processes and switching on catabolic pathways in response to energy depletion. Here, we show that AMPK...