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Marc Schweneker

Explore the profile of Marc Schweneker including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1089
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Recent Articles
1.
Hinterberger M, Endt K, Bathke B, Habjan M, Heiseke A, Schweneker M, et al.
Sci Rep . 2023 Mar; 13(1):5162. PMID: 36997583
The induction of antiviral innate immunity by systemic immunization with live virus can be employed to positively impact the response to therapeutic vaccination. We previously demonstrated that systemic immunization with...
2.
Locher S, Schweneker M, Hausmann J, Zimmer G
J Gen Virol . 2018 Jun; 99(7):866-879. PMID: 29869979
Vesicular stomatitis virus (VSV) expressing the Ebola virus (EBOV) glycoprotein (GP) in place of the VSV glycoprotein G (VSV/EBOV-GP) is a promising EBOV vaccine candidate which has already entered clinical...
3.
Schweneker M, Laimbacher A, Zimmer G, Wagner S, Schraner E, Wolferstatter M, et al.
J Virol . 2017 Mar; 91(11). PMID: 28331098
There are currently no approved therapeutics or vaccines to treat or protect against the severe hemorrhagic fever and death caused by Ebola virus (EBOV). Ebola virus-like particles (EBOV VLPs) consisting...
4.
Wolferstatter M, Schweneker M, Spath M, Lukassen S, Klingenberg M, Brinkmann K, et al.
J Virol . 2014 Oct; 88(24):14396-411. PMID: 25297997
Unlabelled: Double-stranded RNA (dsRNA) is an important molecular pattern associated with viral infection and is detected by various extra- and intracellular recognition molecules. Poxviruses have evolved to avoid producing dsRNA...
5.
Schweneker K, Gorka O, Schweneker M, Poeck H, Tschopp J, Peschel C, et al.
Immunobiology . 2012 Aug; 218(4):664-73. PMID: 22921586
The success of a vaccine consists in the induction of an innate immune response and subsequent activation of the adaptive immune system. Because antigens are usually not immunogenic, the addition...
6.
Schweneker M, Lukassen S, Spath M, Wolferstatter M, Babel E, Brinkmann K, et al.
J Virol . 2011 Dec; 86(4):2323-36. PMID: 22171261
Sustained activation of the Raf/MEK/extracellular signal-regulated kinase (ERK) pathway in infected cells has been shown to be crucial for full replication efficiency of orthopoxviruses in cell culture. In infected cells,...
7.
Baur K, Brinkmann K, Schweneker M, Patzold J, Meisinger-Henschel C, Hermann J, et al.
J Virol . 2010 Jun; 84(17):8743-52. PMID: 20538860
Efficient T-cell responses against recombinant antigens expressed by vaccinia virus vectors require expression of these antigens in the early phase of the virus replication cycle. The kinetics of recombinant gene...
8.
Pechloff K, Holch J, Ferch U, Schweneker M, Brunner K, Kremer M, et al.
J Exp Med . 2010 May; 207(5):1031-44. PMID: 20439541
Peripheral T cell lymphomas (PTCLs) are highly aggressive malignancies with poor prognosis. Their molecular pathogenesis is not well understood and small animal models for the disease are lacking. Recently, the...
9.
Contreras X, Schweneker M, Chen C, McCune J, Deeks S, Martin J, et al.
J Biol Chem . 2009 Jan; 284(11):6782-9. PMID: 19136668
Human immunodeficiency virus (HIV) persists in a latent form in infected individuals treated effectively with highly active antiretroviral therapy (HAART). In part, these latent proviruses account for the rebound in...
10.
Jones R, Ndhlovu L, Barbour J, Sheth P, Jha A, Long B, et al.
J Exp Med . 2008 Nov; 205(12):2763-79. PMID: 19001139
Progressive loss of T cell functionality is a hallmark of chronic infection with human immunodeficiency virus 1 (HIV-1). We have identified a novel population of dysfunctional T cells marked by...