Marc R Block
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Explore the profile of Marc R Block including associated specialties, affiliations and a list of published articles.
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29
Citations
1003
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Recent Articles
1.
Block M, Brunner M, Ziegelmeyer T, Lallemand D, Pezet M, Chevalier G, et al.
J Biol Chem
. 2020 Jul;
295(39):13474-13487.
PMID: 32690605
Yes-associated protein (YAP) signaling has emerged as a crucial pathway in several normal and pathological processes. Although the main upstream effectors that regulate its activity have been extensively studied, the...
2.
Brunner M, Mandier N, Gautier T, Chevalier G, Ribba A, Guardiola P, et al.
PLoS One
. 2018 Apr;
13(4):e0196021.
PMID: 29677202
Osteoblast differentiation is a highly regulated process that requires coordinated information from both soluble factors and the extracellular matrix. Among these extracellular stimuli, chemical and physical properties of the matrix...
3.
Sabra H, Brunner M, Mandati V, Wehrle-Haller B, Lallemand D, Ribba A, et al.
J Biol Chem
. 2017 Oct;
292(47):19179-19197.
PMID: 28972170
Cell adhesion to the extracellular matrix or to surrounding cells plays a key role in cell proliferation and differentiation and is critical for proper tissue homeostasis. An important pathway in...
4.
Fiorucci S, Lin X, Sadoul K, Fournet G, Bouvard D, Vinogradova O, et al.
PLoS One
. 2015 Oct;
10(10):e0141205.
PMID: 26509443
We previously reported the anti-migratory function of 3-aryl-2-quinolone derivatives, chemically close to flavonoids (Joseph et al., 2002). Herein we show that 3-arylquinoline or 3-aryl-2-quinolone derivatives disrupt cell adhesion in a...
5.
Gabriel M, Balle D, Bigault S, Pornin C, Getin S, Perraut F, et al.
Sci Rep
. 2015 Oct;
5:14532.
PMID: 26459014
Video microscopy offers outstanding capabilities to investigate the dynamics of biological and pathological mechanisms in optimal culture conditions. Contact imaging is one of the simplest imaging architectures to digitally record...
6.
Jing J, Fournier A, Szarpak-Jankowska A, Block M, Auzely-Velty R
Biomacromolecules
. 2015 Jan;
16(3):715-22.
PMID: 25629300
In this work, cell-responsive polysaccharide hydrogels were prepared by a simple procedure based on the sequential bioconjugation and cross-linking of the polysaccharide backbone with bioactive peptides and poly(ethylene glycol)-bis(thiol) (PEG-(SH)2),...
7.
Brunner M, Jurdic P, Tuckerman J, Block M, Bouvard D
Int Rev Cell Mol Biol
. 2013 Jul;
305:1-68.
PMID: 23890379
Mineralized tissues that are protective scaffolds in the most primitive species have evolved and acquired more specific functions in modern animals. These are as diverse as support in locomotion, ion...
8.
Millon-Fremillon A, Brunner M, Abed N, Collomb E, Ribba A, Block M, et al.
J Biol Chem
. 2013 May;
288(28):20248-60.
PMID: 23720740
Focal adhesion turnover during cell migration is an integrated cyclic process requiring tight regulation of integrin function. Interaction of integrin with its ligand depends on its activation state, which is...
9.
Hachet E, Van Den Berghe H, Bayma E, Block M, Auzely-Velty R
Biomacromolecules
. 2012 May;
13(6):1818-27.
PMID: 22559074
Hyaluronic acid (HA) is a natural polysaccharide abundant in biological tissues with excellent potential for constructing synthetic extracellular matrix analogues. In this work, we established a simple and dependable approach...
10.
Brunner M, Millon-Fremillon A, Chevalier G, Nakchbandi I, Mosher D, Block M, et al.
J Cell Biol
. 2011 Jul;
194(2):307-22.
PMID: 21768292
The morphogenetic and differentiation events required for bone formation are orchestrated by diffusible and insoluble factors that are localized within the extracellular matrix. In mice, the deletion of ICAP-1, a...