Marc P Stemmler
Overview
Explore the profile of Marc P Stemmler including associated specialties, affiliations and a list of published articles.
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4480
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Recent Articles
11.
Stehr A, Wang G, Demmler R, Stemmler M, Krug J, Tripal P, et al.
J Pathol
. 2021 Dec;
256(4):455-467.
PMID: 34939675
Neutrophil extracellular traps (NETs) are extracellular structures, composed of nuclear DNA and various proteins released from neutrophils. Evidence is growing that NETs exert manifold functions in infection, immunity and cancer....
12.
van Roey R, Brabletz T, Stemmler M, Armstark I
Front Cell Dev Biol
. 2021 Dec;
9:753456.
PMID: 34888306
Pancreatic cancer is a very aggressive disease with 5-year survival rates of less than 10%. The constantly increasing incidence and stagnant patient outcomes despite changes in treatment regimens emphasize the...
13.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al.
Nat Rev Mol Cell Biol
. 2021 Oct;
22(12):834.
PMID: 34654908
No abstract available.
14.
Wang J, Farkas C, Benyoucef A, Carmichael C, Haigh K, Wong N, et al.
PLoS Biol
. 2021 Sep;
19(9):e3001394.
PMID: 34550965
The ZEB2 transcription factor has been demonstrated to play important roles in hematopoiesis and leukemic transformation. ZEB1 is a close family member of ZEB2 but has remained more enigmatic concerning...
15.
Brabletz S, Schuhwerk H, Brabletz T, Stemmler M
EMBO J
. 2021 Aug;
40(18):e108647.
PMID: 34459003
The process of epithelial-mesenchymal transition (EMT) is fundamental for embryonic morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire mesenchymal features, and become motile. In cancer, this program is...
16.
Gupta B, Errington A, Jimenez-Pascual A, Eftychidis V, Brabletz S, Stemmler M, et al.
Cell Rep
. 2021 Aug;
36(8):109588.
PMID: 34433050
Radial glia-like (RGL) stem cells persist in the adult mammalian hippocampus, where they generate new neurons and astrocytes throughout life. The process of adult neurogenesis is well documented, but cell-autonomous...
17.
Losada M, Pauler M, Vandamme N, Goossens S, Berx G, Leppkes M, et al.
Cell Death Discov
. 2021 Jun;
7(1):138.
PMID: 34112759
The pancreas is comprised of exocrine and endocrine compartments releasing digestive enzymes into the duodenum and regulating blood glucose levels by insulin and glucagon release. Tissue homeostasis is depending on...
18.
Ruh M, Stemmler M, Frisch I, Fuchs K, van Roey R, Kleemann J, et al.
J Pathol
. 2021 Mar;
254(2):199-211.
PMID: 33675037
Osteosarcoma is an often-fatal mesenchyme-derived malignancy in children and young adults. Overexpression of EMT-transcription factors (EMT-TFs) has been associated with poor clinical outcome. Here, we demonstrated that the EMT-TF ZEB1...
19.
Almotiri A, Alzahrani H, Menendez-Gonzalez J, Abdelfattah A, Alotaibi B, Saleh L, et al.
J Clin Invest
. 2020 Oct;
131(1).
PMID: 33108352
Zeb1, a zinc finger E-box binding homeobox epithelial-mesenchymal transition (EMT) transcription factor, confers properties of "stemness," such as self-renewal, in cancer. Yet little is known about the function of Zeb1...
20.
Feldker N, Ferrazzi F, Schuhwerk H, Widholz S, Guenther K, Frisch I, et al.
EMBO J
. 2020 Jul;
39(17):e103209.
PMID: 32692442
Invasion, metastasis and therapy resistance are the major cause of cancer-associated deaths, and the EMT-inducing transcription factor ZEB1 is a crucial stimulator of these processes. While work on ZEB1 has...