Marc P Stemmler
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Explore the profile of Marc P Stemmler including associated specialties, affiliations and a list of published articles.
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60
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4480
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Recent Articles
1.
Schultz H, Zhou X, Alonso C, Ongaro L, Lin Y, Loka M, et al.
Endocrinology
. 2024 Sep;
165(10).
PMID: 39248143
Luteinizing hormone (LH), a heterodimeric glycoprotein produced by pituitary gonadotrope cells, regulates gonadal function. Hypothalamic gonadotropin-releasing hormone (GnRH) stimulates LH synthesis and secretion. GnRH induces LHβ subunit (Lhb) expression via...
2.
Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkas K, Bindel N, et al.
Nat Cell Biol
. 2024 Jul;
26(9):1470-1481.
PMID: 39009641
Therapy resistance and metastasis, the most fatal steps in cancer, are often triggered by a (partial) activation of the epithelial-mesenchymal transition (EMT) programme. A mesenchymal phenotype predisposes to ferroptosis, a...
3.
Menche C, Schuhwerk H, Armstark I, Gupta P, Fuchs K, van Roey R, et al.
EMBO Rep
. 2024 Jun;
25(8):3406-3431.
PMID: 38937629
The EMT-transcription factor ZEB1 is heterogeneously expressed in tumor cells and in cancer-associated fibroblasts (CAFs) in colorectal cancer (CRC). While ZEB1 in tumor cells regulates metastasis and therapy resistance, its...
4.
Zhang S, Yun D, Yang H, Eckstein M, Daw Elbait G, Zhou Y, et al.
Cell Death Discov
. 2024 Mar;
10(1):124.
PMID: 38461159
Pancreatic cancer is a malignant tumor of the digestive system. It is highly aggressive, easily metastasizes, and extremely difficult to treat. This study aimed to analyze the genes that might...
5.
Almotiri A, Abdelfattah A, Storch E, Stemmler M, Brabletz S, Brabletz T, et al.
Exp Hematol
. 2024 Feb;
134:104177.
PMID: 38336135
Emerging evidence implicates the epithelial-mesenchymal transition transcription factor Zeb1 as a critical regulator of hematopoietic stem cell (HSC) differentiation. Whether Zeb1 regulates long-term maintenance of HSC function remains an open...
6.
Savagner P, Brabletz T, Cheng C, Gilles C, Hong T, Polette M, et al.
Cells Tissues Organs
. 2024 Jan;
213(4):297-303.
PMID: 38194935
This report summarizes the 10th biennial meeting of The Epithelial Mesenchymal Transition International Association (TEMTIA), that took place in Paris on November 7-10, 2022. It provides a short but comprehensive...
7.
Zhu L, Tang Y, Li X, Kerk S, Lyssiotis C, Feng W, et al.
EMBO J
. 2023 Feb;
42(7):e111148.
PMID: 36843552
Osteoclasts are bone-resorbing polykaryons responsible for skeletal remodeling during health and disease. Coincident with their differentiation from myeloid precursors, osteoclasts undergo extensive transcriptional and metabolic reprogramming in order to acquire...
8.
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, et al.
Cell Rep
. 2022 Dec;
41(11):111819.
PMID: 36516781
The DNA damage response (DDR) and epithelial-to-mesenchymal transition (EMT) are two crucial cellular programs in cancer biology. While the DDR orchestrates cell-cycle progression, DNA repair, and cell death, EMT promotes...
9.
Bijlsma M, Bailey P, Stemmler M
Front Cell Dev Biol
. 2022 Apr;
10:875836.
PMID: 35433705
No abstract available.
10.
Duethorn B, Groll F, Rieger B, Drexler H, Brinkmann H, Kremer L, et al.
Nat Commun
. 2022 Feb;
13(1):610.
PMID: 35105859
Lima1 is an extensively studied prognostic marker of malignancy and is also considered to be a tumour suppressor, but its role in a developmental context of non-transformed cells is poorly...