Marc Loriaux
Overview
Explore the profile of Marc Loriaux including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
28
Citations
1266
Followers
0
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Recent Articles
1.
Raymond L, Funk T, Braziel R, Fan G, Gatter K, Loriaux M, et al.
Br J Haematol
. 2020 Apr;
189(4):e160-e164.
PMID: 32242922
No abstract available.
2.
Edwards 5th D, Watanabe-Smith K, Rofelty A, Damnernsawad A, Laderas T, Lamble A, et al.
Blood
. 2018 Nov;
133(6):588-599.
PMID: 30425048
To identify new therapeutic targets in acute myeloid leukemia (AML), we performed small-molecule and small-interfering RNA (siRNA) screens of primary AML patient samples. In 23% of samples, we found sensitivity...
3.
Jenkins C, Luty S, Maxson J, Eide C, Abel M, Togiai C, et al.
Sci Signal
. 2018 Jul;
11(539).
PMID: 30018082
The protein tyrosine phosphatase PTPN11 is implicated in the pathogenesis of juvenile myelomonocytic leukemia (JMML), acute myeloid leukemia (AML), and other malignancies. Activating mutations in PTPN11 increase downstream proliferative signaling...
4.
Scott E, Maziarz R, Spurgeon S, Medvedova E, Gajewski J, Reasor-Heard S, et al.
Haematologica
. 2017 Apr;
102(7):e261-e265.
PMID: 28385778
No abstract available.
5.
Leonard J, Rowley J, Eide C, Traer E, Hayes-Lattin B, Loriaux M, et al.
Sci Transl Med
. 2016 Sep;
8(354):354ra114.
PMID: 27582059
Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) remains a challenge. Although the addition of targeted tyrosine kinase inhibitors (TKIs) to standard cytotoxic therapy has greatly improved upfront treatment, treatment-related...
6.
Viola S, Traer E, Huan J, Hornick N, Tyner J, Agarwal A, et al.
Br J Haematol
. 2015 Jun;
172(6):983-6.
PMID: 26095727
No abstract available.
7.
YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway
Chang B, Johnson K, LaTocha D, Rowley J, Bryant J, Burke R, et al.
J Hematol Oncol
. 2015 Apr;
8:39.
PMID: 25895498
Background: Novel-targeted therapies are in rapid development for the treatment of acute lymphoblastic leukemia (ALL) to overcome resistance and decrease toxicity. Survivin, a member of the inhibitor of apoptosis gene...
8.
Emerson G, Lim L, Loriaux M, Yassin H, Flaxel C, Smith J, et al.
Retin Cases Brief Rep
. 2014 Nov;
3(2):197-9.
PMID: 25391074
Purpose: To describe an ocular manifestation of Castleman disease, a rare lymphoproliferative disorder characterized by sheets of abundant plasma cells in the interfollicular spaces of lymph nodes, most commonly in...
9.
Dickerson E, Marley K, Edris W, Tyner J, Schalk V, MacDonald V, et al.
Transl Oncol
. 2013 Apr;
6(2):158-68.
PMID: 23544168
Hemangiosarcoma, a natural model of human angiosarcoma, is an aggressive vascular tumor diagnosed commonly in dogs. The documented expression of several receptor tyrosine kinases (RTKs) by these tumors makes them...
10.
Agarwal A, Fleischman A, Petersen C, MacKenzie R, Luty S, Loriaux M, et al.
Blood
. 2012 Aug;
120(13):2658-68.
PMID: 22889761
Sequestration in the bone marrow niche may allow leukemic stem cells to evade exposure to drugs. Because the CXCR4/SDF-1 axis is an important mechanism of leukemic stem cell interaction with...