Marc Lewitzky
Overview
Explore the profile of Marc Lewitzky including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
400
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Recent Articles
1.
Plucarova J, Jansen S, Narasimhan S, Lanikova A, Lewitzky M, Feller S, et al.
J Biol Chem
. 2022 Aug;
298(10):102384.
PMID: 35987383
Microtubule-associated protein 2 (MAP2) is an important neuronal target of extracellular signal-regulated kinase 2 (ERK2) involved in Raf signaling pathways, but mechanistic details of MAP2 phosphorylation are unclear. Here, we...
2.
Gruber T, Lewitzky M, Machner L, Weininger U, Feller S, Balbach J
J Mol Biol
. 2021 Dec;
434(5):167407.
PMID: 34929201
Intrinsically disordered proteins (IDPs) are an important class of proteins which lack tertiary structure elements. Their dynamic properties can depend on reversible post-translational modifications and the complex cellular milieu, which...
3.
Bongartz H, Gille K, Hessenkemper W, Mandel K, Lewitzky M, Feller S, et al.
Cell Commun Signal
. 2019 Oct;
17(1):135.
PMID: 31651330
Background: Cytokine-dependent activation of signalling pathways is tightly orchestrated. The spatiotemporal activation of signalling pathways dictates the specific physiological responses to cytokines. Dysregulated signalling accounts for neoplastic, developmental, and inflammatory...
4.
Feller S, Lewitzky M
Cell Commun Signal
. 2016 Sep;
14(1):24.
PMID: 27677261
Non-protein coding RNAs in different flavors (miRNAs, piRNAs, snoRNAs, lncRNAs, SHOT-RNAs), exosomes, large oncosomes, exoDNA and now tumor-educated platelets (TEPs) have emerged as crucial signal transmitting, transporting and regulating devices...
5.
Krieger J, Fusco G, Lewitzky M, Simister P, Marchant J, Camilloni C, et al.
Biophys J
. 2014 Apr;
106(8):1771-9.
PMID: 24739176
There is a growing interest in understanding the properties of intrinsically disordered proteins (IDPs); however, the characterization of these states remains an open challenge. IDPs appear to have functional roles...
6.
Feller S, Lewitzky M
Cell Commun Signal
. 2012 Nov;
10(1):31.
PMID: 23110718
DNAs and proteins are major classes of biomolecules that differ in many aspects. However, a considerable number of their members also share a common architectural feature that enables the assembly...
7.
Lewitzky M, Simister P, Feller S
FEBS Lett
. 2012 Jun;
586(17):2740-50.
PMID: 22710161
The molecular architectures of intracellular signaling networks are largely unknown. Understanding their design principles and mechanisms of processing information is essential to grasp the molecular basis of virtually all biological...
8.
Feller S, Lewitzky M
Cell Commun Signal
. 2012 Jun;
10(1):15.
PMID: 22697256
A considerable number of soluble proteins in cells that biochemists try to analyze are difficult to handle because they seem to behave like sponges that 'suck up' many other proteins....
9.
Pietrek M, Brinkmann M, Glowacka I, Enlund A, Havemeier A, Dittrich-Breiholz O, et al.
J Virol
. 2010 Jun;
84(16):8231-40.
PMID: 20534855
The Kaposi's sarcoma-associated herpesvirus (KSHV) contains several open reading frames (ORFs) that encode proteins capable of initiating and modulating cellular signaling pathways. Among them is ORF K15, encoding a 12-transmembrane-spanning...
10.
Harkiolaki M, Tsirka T, Lewitzky M, Simister P, Joshi D, Bird L, et al.
Structure
. 2009 Jun;
17(6):809-22.
PMID: 19523899
Grb2 and Gab2 form a complex implicated in normal cell signaling and cancer development. Binding of the Grb2SH3C domain to Gab2 is essential for the interaction, but molecular details remained...