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Marc K Halushka

Explore the profile of Marc K Halushka including associated specialties, affiliations and a list of published articles. Areas
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Articles 194
Citations 8275
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Recent Articles
1.
Halushka M, dAmati G, Bois M, De Gaspari M, Giordano C, Klingel K, et al.
Cardiovasc Pathol . 2025 Mar; :107733. PMID: 40089045
Lymphocytic myocarditis is a serious disease with significant morbidity and mortality. Cardiovascular pathology has an important role in its diagnosis, a diagnosis historically made using the presence of a lymphocytic...
2.
Liu X, Halushka M
Lab Invest . 2024 Dec; 105(2):102206. PMID: 39647608
Over the past decade, a scientific field has been developed demonstrating microRNAs (miRNAs) to be actively sorted into extracellular vesicles via specific nucleotide motifs that interact with discrete RNA-binding proteins....
3.
Baran A, Patil A, Aparicio-Puerta E, Halushka M, McCall M
bioRxiv . 2024 Jul; PMID: 39071300
MicroRNA-seq data is produced by aligning small RNA sequencing reads of different miRNA transcript isoforms, called isomiRs, to known microRNAs. Aggregation to microRNA-level counts discards information and violates core assumptions...
4.
Nieuwenhuis T, Giles H, Arking J, Patil A, Shi W, McCall M, et al.
Lab Invest . 2024 Apr; 104(6):102069. PMID: 38670317
Tissue gene expression studies are impacted by biological and technical sources of variation, which can be broadly classified into wanted and unwanted variation. The latter, if not addressed, results in...
5.
Yang X, Delsante M, Daneshpajouhnejad P, Fenaroli P, Mandell K, Wang X, et al.
Lab Invest . 2024 Jan; 104(5):100336. PMID: 38266922
Chronic kidney disease progresses through the replacement of functional tissue compartments with fibrosis, a maladaptive repair process. Shifting kidney repair toward a physiologically intact architecture, rather than fibrosis, is key...
6.
Patil A, McCall M, Halushka M
NAR Genom Bioinform . 2024 Jan; 6(1):lqad112. PMID: 38213836
Altered open chromatin regions, impacting gene expression, is a feature of some human disorders. We discovered it is possible to detect global changes in genomically-related adjacent gene co-expression within single...
7.
Ziogos E, Chelko S, Harb T, Engel M, Vavuranakis M, Landim-Vieira M, et al.
Eur Heart J Cardiovasc Pharmacother . 2023 Jul; 9(7):636-646. PMID: 37468450
Aims: Platelet activation and endothelial dysfunction contribute to adverse outcomes in patients with acute coronary syndromes (ACS). The goals of this study were to assess the impact of proprotein convertase...
8.
Halushka M
Cardiovasc Pathol . 2023 Jun; 66:107555. PMID: 37339723
No abstract available.
9.
Jani V, Aslam M, Fenwick A, Ma W, Gong H, Milburn G, et al.
Circulation . 2023 May; 147(25):1919-1932. PMID: 37194598
Background: Right ventricular (RV) contractile dysfunction commonly occurs and worsens outcomes in patients with heart failure with reduced ejection fraction and pulmonary hypertension (HFrEF-PH). However, such dysfunction often goes undetected...
10.
Jenike A, Jenike K, Peterson K, Fromm B, Halushka M
Evol Dev . 2023 May; 25(3):226-239. PMID: 37157156
The evolution of specialized cell-types is a long-standing interest of biologists, but given the deep time-scales very difficult to reconstruct or observe. microRNAs have been linked to the evolution of...