Marat Mufteev
Overview
Explore the profile of Marat Mufteev including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
209
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Recent Articles
1.
Gordillo-Sampedro S, Antounians L, Wei W, Mufteev M, Lendemeijer B, Kushner S, et al.
Mol Cell Neurosci
. 2024 Apr;
129:103933.
PMID: 38663691
Astrocytes are in constant communication with neurons during the establishment and maturation of functional networks in the developing brain. Astrocytes release extracellular vesicles (EVs) containing microRNA (miRNA) cargo that regulates...
2.
Rodrigues D, Mufteev M, Yuki K, Narula A, Wei W, Piekna A, et al.
Nat Commun
. 2023 Apr;
14(1):1896.
PMID: 37019888
Transcriptional changes in Rett syndrome (RTT) are assumed to directly correlate with steady-state mRNA levels, but limited evidence in mice suggests that changes in transcription can be compensated by post-transcriptional...
3.
Mufteev M, Rodrigues D, Yuki K, Narula A, Wei W, Piekna A, et al.
bioRxiv
. 2023 Mar;
PMID: 36909614
The contribution of mRNA half-life is commonly overlooked when examining changes in mRNA abundance during development. mRNA levels of some genes are regulated by transcription rate only, but others may...
4.
Mok R, Zhang W, Sheikh T, Pradeepan K, Fernandes I, DeJong L, et al.
Transl Psychiatry
. 2022 Oct;
12(1):450.
PMID: 36253345
Rett syndrome (RTT) is a severe neurodevelopmental disorder primarily caused by heterozygous loss-of-function mutations in the X-linked gene MECP2 that is a global transcriptional regulator. Mutations in the methyl-CpG binding...
5.
Subramanian A, Hall M, Hou H, Mufteev M, Yu B, Yuki K, et al.
Sci Adv
. 2021 Dec;
7(51):eabh0562.
PMID: 34919436
Alternative polyadenylation of mRNA has important but poorly understood roles in development and cancer. Activating mutations in the Ras oncogene are common drivers of many human cancers. From a screen...
6.
Byres L, Mufteev M, Yuki K, Wei W, Piekna A, Wilson M, et al.
Mol Biol Rep
. 2021 Aug;
48(9):6349-6361.
PMID: 34410578
Background: Neuronal development is a tightly controlled process involving multi-layered regulatory mechanisms. While transcriptional pathways regulating neurodevelopment are well characterized, post-transcriptional programs are still poorly understood. TIA1 is an RNA-binding...
7.
Rodrigues D, Mufteev M, Ellis J
STAR Protoc
. 2020 Dec;
2(1):100229.
PMID: 33364619
Translation regulation is a fundamental step in gene regulation with critical roles in neurodevelopment. Here, we describe three protocols to calculate the ribosomal-engagement levels of the transcriptome from -derived neuronal...
8.
Rodrigues D, Mufteev M, Ellis J
Hum Mol Genet
. 2020 Jul;
29(R1):R89-R99.
PMID: 32681172
The methyl-CpG-binding protein 2 (MECP2) is a critical global regulator of gene expression. Mutations in MECP2 cause neurodevelopmental disorders including Rett syndrome (RTT). MECP2 exon 2 is spliced into two...
9.
Ross P, Mok R, Smith B, Rodrigues D, Mufteev M, Scherer S, et al.
Mol Autism
. 2020 May;
11(1):33.
PMID: 32398033
Genetic factors contribute to the development of autism spectrum disorder (ASD), and although non-protein-coding regions of the genome are being increasingly implicated in ASD, the functional consequences of these variants...
10.
Rodrigues D, Mufteev M, Weatheritt R, Djuric U, Ha K, Ross P, et al.
Cell Rep
. 2020 Mar;
30(12):4179-4196.e11.
PMID: 32209477
Regulation of translation during human development is poorly understood, and its dysregulation is associated with Rett syndrome (RTT). To discover shifts in mRNA ribosomal engagement (RE) during human neurodevelopment, we...