Mar Fernandez-Borja
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Explore the profile of Mar Fernandez-Borja including associated specialties, affiliations and a list of published articles.
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26
Citations
761
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Recent Articles
1.
Arts J, Mahlandt E, Schimmel L, Gronloh M, Niet S, Klein B, et al.
Front Immunol
. 2021 Jun;
12:667213.
PMID: 34084168
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on...
2.
Kovacevic I, Sakaue T, Majolee J, Pronk M, Maekawa M, Geerts D, et al.
J Cell Biol
. 2018 Jan;
217(3):1015-1032.
PMID: 29358211
RhoGTPases control endothelial cell (EC) migration, adhesion, and barrier formation. Whereas the relevance of RhoA for endothelial barrier function is widely accepted, the role of the RhoA homologue RhoB is...
3.
Richardson D, Fernandez-Borja M
Bioarchitecture
. 2016 Jan;
5(5-6):61-9.
PMID: 26744925
Leukocyte traffic out of the blood stream is crucial for an adequate immune response. Leukocyte extravasation is critically dependent on the binding of leukocyte integrins to their endothelial counterreceptors. This...
4.
Richardson D, Tol S, Valle-Encinas E, Pleguezuelos C, Bierings R, Geerts D, et al.
J Cell Sci
. 2015 Jul;
128(16):3018-29.
PMID: 26159734
The broad tissue distribution and evolutionary conservation of the glycosylphosphatidylinositol (GPI)-anchored prion protein (PrP, also known as PRNP) suggests that it plays a role in cellular homeostasis. Given that integrin...
5.
van Breevoort D, Snijders A, Hellen N, Weckhuysen S, van Hooren K, Eikenboom J, et al.
Blood
. 2014 Apr;
123(20):3185-94.
PMID: 24700782
Vascular endothelial cells contain unique rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs), which contain the hemostatic protein von Willebrand factor (VWF) and a cocktail of angiogenic and inflammatory mediators. We...
6.
van Hooren K, Spijkers L, van Breevoort D, Fernandez-Borja M, Bierings R, van Buul J, et al.
PLoS One
. 2014 Mar;
9(3):e91346.
PMID: 24632890
Sphingosine-1-phosphate (S1P) is an agonist for five distinct G-protein coupled receptors, that is released by platelets, mast cells, erythrocytes and endothelial cells. S1P promotes endothelial cell barrier function and induces...
7.
Kroon J, Tol S, van Amstel S, Elias J, Fernandez-Borja M
PLoS One
. 2013 Oct;
8(9):e75031.
PMID: 24086429
The inflammatory response of endothelial cells triggered by cytokines such as TNFα and IL1β plays a pivotal role in innate immunity. Upon pro-inflammatory cytokine stimulation, endothelial cells produce chemokines and...
8.
de Kreuk B, Schaefer A, Anthony E, Tol S, Fernandez-Borja M, Geerts D, et al.
PLoS One
. 2013 Oct;
8(9):e73962.
PMID: 24086303
The human minor Histocompatibility Antigen HMHA-1 is a major target of immune responses after allogeneic stem cell transplantation applied for the treatment of leukemia and solid tumors. The restriction of...
9.
Fernandez-Borja M
Cell Res
. 2012 Aug;
22(10):1426-8.
PMID: 22890385
Endothelial cell adhesion to the extracellular matrix regulates migration and outgrowth of blood vessels during angiogenesis. Cell adhesion is mediated by integrins, which transduce signals from the extracellular environment into...
10.
van Agtmaal E, Bierings R, Dragt B, Leyen T, Fernandez-Borja M, Horrevoets A, et al.
PLoS One
. 2012 Jun;
7(6):e38399.
PMID: 22715381
Background: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we...