Manuel Sellner
Overview
Explore the profile of Manuel Sellner including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
168
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0
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Recent Articles
1.
Reinhardt J, Schertler L, Bussmann H, Sellner M, Smiesko M, Boonen G, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519010
Pre-clinical studies suggest that extracts prepared from the fruits of (VAC) interact with dopamine D2 receptors, leading to reduced prolactin secretion. In previous experiments, dopaminergic activity was mostly evaluated using...
2.
Inderbinen S, Kley M, Zogg M, Sellner M, Fischer A, Kedzierski J, et al.
Toxicology
. 2022 Mar;
471:153159.
PMID: 35337918
Retinoic acid-related orphan receptor γt (RORγt) regulates immune responses and its impaired function contributes to inflammatory and autoimmune diseases and may promote skin cancer. Synthetic inverse RORγt agonists block the...
3.
Fischer A, Bardakci F, Sellner M, Lill M, Smiesko M
J Biomol Struct Dyn
. 2022 Jan;
41(5):1639-1648.
PMID: 35068382
The three subtypes of estrogen-related receptors ERR, ERR, and ERR are nuclear receptors mediating metabolic processes in various tissues such as the skeletal muscle, fat tissue, bone, and liver. Although...
4.
Papaj K, Spychalska P, Kapica P, Fischer A, Nowak J, Bzowka M, et al.
PLoS One
. 2022 Jan;
17(1):e0262482.
PMID: 35015795
Based on previous large-scale in silico screening several factor Xa inhibitors were proposed to potentially inhibit SARS-CoV-2 Mpro. In addition to their known anticoagulants activity this potential inhibition could have...
5.
Fischer A, Sellner M, Mitusinska K, Bzowka M, Lill M, Gora A, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33669738
The pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious global health threat. Since no specific therapeutics are available, researchers around the world screened compounds to...
6.
Fischer A, Smiesko M, Sellner M, Lill M
J Med Chem
. 2021 Feb;
64(5):2489-2500.
PMID: 33617246
Molecular docking is a computational method widely used in drug discovery. Due to the inherent inaccuracies of molecular docking, visual inspection of binding modes is a crucial routine in the...
7.
Sellner M, Fischer A, Don C, Smiesko M
Int J Mol Sci
. 2021 Jan;
22(3).
PMID: 33498551
Oxidative reactions catalyzed by Cytochrome P450 enzymes (CYPs), which constitute the most relevant group of drug-metabolizing enzymes, are enabled by their redox partner Cytochrome P450 reductase (CPR). Both proteins are...
8.
Fischer A, Sellner M, Neranjan S, Smiesko M, Lill M
Int J Mol Sci
. 2020 May;
21(10).
PMID: 32455534
The rapid outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China followed by its spread around the world poses a serious global concern for public health....