Manu Vanaerschot
Overview
Explore the profile of Manu Vanaerschot including associated specialties, affiliations and a list of published articles.
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53
Citations
1607
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Recent Articles
1.
Munjita S, Kalonda A, Mubemba B, Vanaerschot M, Tato C, Mwakibete L, et al.
Infect Ecol Epidemiol
. 2025 Jan;
15(1):2441537.
PMID: 39764202
Background: Infectious disease agents pose significant threats to humans, wildlife, and livestock, with rodents carrying a third of these agents, many linked to human diseases. However, the range of pathogens...
2.
Luth M, Godinez-Macias K, Chen D, Okombo J, Thathy V, Cheng X, et al.
Science
. 2024 Nov;
386(6725):eadk9893.
PMID: 39607932
Surveillance of drug resistance and the discovery of novel targets-key objectives in the fight against malaria-rely on identifying resistance-conferring mutations in parasites. Current approaches, while successful, require laborious experimentation or...
3.
Khan W, Kabir F, Kanwar S, Aziz F, Muneer S, Kalam A, et al.
BMJ Glob Health
. 2023 Nov;
8(11).
PMID: 37984892
Next-generation sequencing technology has revolutionised pathogen surveillance over the last two decades. However, the benefits are not equitably distributed, with developing countries lagging far behind in acquiring the required technology...
4.
Munjita S, Moonga G, Mukubesa A, Ndebe J, Mubemba B, Vanaerschot M, et al.
Pathogens
. 2022 Nov;
11(11).
PMID: 36422597
Transmission dynamics and the maintenance of mammarenaviruses in nature are poorly understood. Using metagenomic next-generation sequencing (mNGS) and RT-PCR, we investigated the presence of mammarenaviruses and co-infecting helminths in various...
5.
Yek C, Pacheco A, Vanaerschot M, Bohl J, Fahsbender E, Aranda-Diaz A, et al.
Front Epidemiol
. 2022 Oct;
2.
PMID: 36247976
Metagenomic next-generation sequencing (mNGS) is the process of sequencing all genetic material in a biological sample. The technique is growing in popularity with myriad applications including outbreak investigation, biosurveillance, and...
6.
Perier C, Nasinghe E, Charles I, Ssetaba L, Ahyong V, Bangs D, et al.
Glob Health Action
. 2022 Jun;
15(1):2062175.
PMID: 35730550
Science education and research have the potential to drive profound change in low- and middle-income countries (LMICs) through encouraging innovation, attracting industry, and creating job opportunities. However, in LMICs, research...
7.
Summers R, Pasaje C, Pisco J, Striepen J, Luth M, Kumpornsin K, et al.
Cell Chem Biol
. 2021 Aug;
29(2):191-201.e8.
PMID: 34348113
We identify the Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS) as a druggable target, using genetic and chemical validation. In vitro evolution of resistance with two antiplasmodial drug-like compounds (MMV019721 and...
8.
Murithi J, Deni I, Pasaje C, Okombo J, Bridgford J, Gnadig N, et al.
Cell Chem Biol
. 2021 Jul;
29(5):824-839.e6.
PMID: 34233174
Widespread Plasmodium falciparum resistance to first-line antimalarials underscores the vital need to develop compounds with novel modes of action and identify new druggable targets. Here, we profile five compounds that...
9.
Peng J, Liu J, Mann S, Mitchell A, Laurie M, Sunshine S, et al.
Clin Infect Dis
. 2021 Mar;
74(1):32-39.
PMID: 33788923
Background: Sequencing of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral genome from patient samples is an important epidemiological tool for monitoring and responding to the pandemic, including the...
10.
Peng J, Mann S, Mitchell A, Liu J, Laurie M, Sunshine S, et al.
medRxiv
. 2021 Mar;
PMID: 33688689
Background: Sequencing of the SARS-CoV-2 viral genome from patient samples is an important epidemiological tool for monitoring and responding to the pandemic, including the emergence of new mutations in specific...