Manu Vanaerschot
Overview
Explore the profile of Manu Vanaerschot including associated specialties, affiliations and a list of published articles.
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53
Citations
1607
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Recent Articles
11.
Miguel-Blanco C, Murithi J, Diez Benavente E, Angrisano F, Sala K, van Schalkwyk D, et al.
Sci Rep
. 2021 Jan;
11(1):1888.
PMID: 33479319
New antimalarial therapeutics are needed to ensure that malaria cases continue to be driven down, as both emerging parasite resistance to frontline chemotherapies and mosquito resistance to current insecticides threaten...
12.
Crawford E, Acosta I, Ahyong V, Anderson E, Arevalo S, Asarnow D, et al.
PLoS Pathog
. 2020 Oct;
16(10):e1008966.
PMID: 33112933
No abstract available.
13.
Vanaerschot M, Mann S, Webber J, Kamm J, Bell S, Bell J, et al.
J Clin Microbiol
. 2020 Oct;
59(1).
PMID: 33067272
No abstract available.
14.
Imamura H, Monsieurs P, Jara M, Sanders M, Maes I, Vanaerschot M, et al.
Sci Rep
. 2020 Sep;
10(1):15043.
PMID: 32929126
Here, we report a pilot study paving the way for further single cell genomics studies in Leishmania. First, the performances of two commercially available kits for Whole Genome Amplification (WGA),...
15.
Saha S, Malaker R, Sajib M, Hasanuzzaman M, Rahman H, Ahmed Z, et al.
Microbiol Resour Announc
. 2020 Jun;
9(24).
PMID: 32527780
The complete genome sequence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) isolate obtained from a nasopharyngeal swab from a patient with COVID-19 in Bangladesh is reported.
16.
Vanaerschot M, Murithi J, Pasaje C, Ghidelli-Disse S, Dwomoh L, Bird M, et al.
Cell Chem Biol
. 2020 May;
27(7):806-816.e8.
PMID: 32359426
The search for antimalarial chemotypes with modes of action unrelated to existing drugs has intensified with the recent failure of first-line therapies across Southeast Asia. Here, we show that the...
17.
Abraham M, Gagaring K, Martino M, Vanaerschot M, Plouffe D, Calla J, et al.
ACS Infect Dis
. 2020 Feb;
6(4):613-628.
PMID: 32078764
Most phenotypic screens aiming to discover new antimalarial chemotypes begin with low cost, high-throughput tests against the asexual blood stage (ABS) of the malaria parasite life cycle. Compounds active against...
18.
Domagalska M, Imamura H, Sanders M, Van den Broeck F, Bhattarai N, Vanaerschot M, et al.
PLoS Negl Trop Dis
. 2019 Dec;
13(12):e0007900.
PMID: 31830038
Whole genome sequencing (WGS) is increasingly used for molecular diagnosis and epidemiology of infectious diseases. Current Leishmania genomic studies rely on DNA extracted from cultured parasites, which might introduce sampling...
19.
Murithi J, Owen E, Istvan E, Lee M, Ottilie S, Chibale K, et al.
Cell Chem Biol
. 2019 Dec;
27(2):158-171.e3.
PMID: 31813848
We report detailed susceptibility profiling of asexual blood stages of the malaria parasite Plasmodium falciparum to clinical and experimental antimalarials, combined with metabolomic fingerprinting. Results revealed a variety of stage-specific...
20.
Antonova-Koch Y, Meister S, Abraham M, Luth M, Ottilie S, Lukens A, et al.
Science
. 2018 Dec;
362(6419).
PMID: 30523084
To discover leads for next-generation chemoprotective antimalarial drugs, we tested more than 500,000 compounds for their ability to inhibit liver-stage development of luciferase-expressing spp. parasites (681 compounds showed a half-maximal...