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Mansour Alkobtawi

Explore the profile of Mansour Alkobtawi including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 57
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Recent Articles
1.
Hirt N, Alkobtawi M, Manchon E, Proust R, Villain E, Lack S, et al.
Int J Biol Macromol . 2025 Feb; 306(Pt 1):141251. PMID: 39986493
Alginate hydrogels are biocompatible and present tunable properties making them ideal for biomedical applications. We designed a novel Ca-Alginate hydrogel and investigated its bioactivity on key component of the immune...
2.
Kotov A, Seal S, Alkobtawi M, Kappes V, Ruiz S, Arbes H, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2311685121. PMID: 38683994
Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of early molecular choices orchestrating the emergence of neural crest heterogeneity from the embryonic ectoderm...
3.
Alkobtawi M, Ngo Q, Chapuis N, Fontaine R, El Khoury M, Tihy M, et al.
Commun Med (Lond) . 2023 Dec; 3(1):177. PMID: 38082066
Background: Pregnant women and their fetuses are particularly susceptible to respiratory pathogens. How they respond to SARS-CoV-2 infection is still under investigation. Methods: We studied the transcriptome and phenotype of...
4.
Alkobtawi M, Pla P, Onteniente B, Seal S, Pingault V, Marlin S, et al.
Stem Cell Res . 2023 Mar; 69:103074. PMID: 36989619
Waardenburg syndrome type 1 (WS1), a rare genetic disease characterized by pigmentation defects and mild craniofacial anomalies often associated with congenital deafness is caused by heterozygous mutations in the PAX3...
5.
du Halgouet A, Darbois A, Alkobtawi M, Mestdagh M, Alphonse A, Premel V, et al.
Immunity . 2023 Jan; 56(1):78-92.e6. PMID: 36630919
Tissue repair processes maintain proper organ function following mechanical or infection-related damage. In addition to antibacterial properties, mucosal associated invariant T (MAIT) cells express a tissue repair transcriptomic program and...
6.
Alkobtawi M, Sbeih M, Souaid K, Ngo Q, Nassar D, Arbes H, et al.
Haematologica . 2022 Nov; 108(7):1920-1933. PMID: 36373248
Leg ulcers are a major complication of sickle cell disease (SCD). They are particularly challenging to treat and innovative therapies are needed. We previously showed that the healing of SCD...
7.
Sbeih M, Oules B, Alkobtawi M, Schwendimann L, Ngo Q, Fontaine R, et al.
Neurobiol Dis . 2022 Oct; 174:105892. PMID: 36240949
Preventing brain cell loss and enhancing tissue repair are crucial objectives to improve the outcome of stroke. Fetal microchimerism has been implicated in brain repair following ischemic stroke in mice....
8.
Alkobtawi M, Pla P, Monsoro-Burq A
Cell Rep . 2021 Jun; 35(12):109289. PMID: 34161771
The spatiotemporal coordination of multiple morphogens is essential for embryonic patterning yet poorly understood. During neural crest (NC) formation, dynamic bone morphogenetic protein (BMP), fibroblast growth factor (FGF), and WNT...
9.
Roussigne M, Wei L, Tsingos E, Kuchling F, Alkobtawi M, Tsalavouta M, et al.
Proc Natl Acad Sci U S A . 2018 Oct; 115(42):E9812-E9821. PMID: 30282743
The ability of cells to collectively interpret surrounding environmental signals underpins their capacity to coordinate their migration in various contexts, including embryonic development and cancer metastasis. One tractable model for...
10.
Alkobtawi M, Ray H, Barriga E, Moreno M, Kerney R, Monsoro-Burq A, et al.
Dev Biol . 2018 Mar; 444 Suppl 1:S202-S208. PMID: 29522707
The neural crest is a multipotent population of cells that originates a variety of cell types. Many animal models are used to study neural crest induction, migration and differentiation, with...