Patrick Pla
Overview
Explore the profile of Patrick Pla including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
471
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0
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Recent Articles
1.
Garcia-Garcia D, Vidal-Gil L, Parain K, Lun J, Audic Y, Chesneau A, et al.
Sci Adv
. 2024 Oct;
10(40):eadp7916.
PMID: 39356769
Unlike mammals, some nonmammalian species recruit Müller glia for retinal regeneration after injury. Identifying the underlying mechanisms may help to foresee regenerative medicine strategies. Using a model of retinitis pigmentosa,...
2.
Alkobtawi M, Pla P, Onteniente B, Seal S, Pingault V, Marlin S, et al.
Stem Cell Res
. 2023 Mar;
69:103074.
PMID: 36989619
Waardenburg syndrome type 1 (WS1), a rare genetic disease characterized by pigmentation defects and mild craniofacial anomalies often associated with congenital deafness is caused by heterozygous mutations in the PAX3...
3.
Scaramuzzino C, Cuoc E, Pla P, Humbert S, Saudou F
Sci Adv
. 2022 Jan;
8(1):eabj8812.
PMID: 34985962
When a neurotrophin binds at the presynapse, it sends survival signals all the way to the nucleus on signaling endosomes. These endosomes fuel their own journey with on-board glycolysis—but how...
4.
Alkobtawi M, Pla P, Monsoro-Burq A
Cell Rep
. 2021 Jun;
35(12):109289.
PMID: 34161771
The spatiotemporal coordination of multiple morphogens is essential for embryonic patterning yet poorly understood. During neural crest (NC) formation, dynamic bone morphogenetic protein (BMP), fibroblast growth factor (FGF), and WNT...
5.
Pla P, Monsoro-Burq A
Dev Biol
. 2018 Jun;
444 Suppl 1:S36-S46.
PMID: 29852131
The neural crest is induced at the edge between the neural plate and the nonneural ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In recent...
6.
Figueiredo A, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, et al.
Development
. 2017 Oct;
144(22):4183-4194.
PMID: 29038306
Neural crest (NC) specification comprises an early phase, initiating immature NC progenitors formation at neural plate stage, and a later phase at neural fold stage, resulting in a functional premigratory...
7.
Pla P, Orvoen S, Saudou F, David D, Humbert S
Front Behav Neurosci
. 2014 May;
8:135.
PMID: 24795586
Huntington's disease (HD) is a neurodegenerative disorder that is best known for its effect on motor control. Mood disturbances such as depression, anxiety, and irritability also have a high prevalence...
8.
Pla P, Orvoen S, Benstaali C, Dodier S, Gardier A, David D, et al.
PLoS One
. 2013 Sep;
8(9):e73902.
PMID: 24019939
Huntington's disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and psychiatric symptoms, including mood disorders such as anxiety and depression. HD is caused by an abnormal polyglutamine...
9.
Ben MBarek K, Pla P, Orvoen S, Benstaali C, Godin J, Gardier A, et al.
J Neurosci
. 2013 May;
33(20):8608-20.
PMID: 23678106
Huntington disease (HD) is associated with early psychiatric symptoms including anxiety and depression. Here, we demonstrate that wild-type huntingtin, the protein mutated in HD, modulates anxiety/depression-related behaviors according to its...
10.
Liot G, Zala D, Pla P, Mottet G, Piel M, Saudou F
J Neurosci
. 2013 Apr;
33(15):6298-309.
PMID: 23575829
Huntingtin (HTT), the protein mutated in Huntington's disease (HD), controls transport of the neurotrophin, brain-derived neurotrophic factor (BDNF), within corticostriatal neurons. Transport and delivery of BDNF to the striatum are...