Manlio Di Cristina
Overview
Explore the profile of Manlio Di Cristina including associated specialties, affiliations and a list of published articles.
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39
Citations
1946
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Recent Articles
11.
Rivera-Cuevas Y, Mayoral J, Di Cristina M, Lawrence A, Olafsson E, Patel R, et al.
PLoS Pathog
. 2021 Dec;
17(12):e1010138.
PMID: 34898650
Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources from the host cell for its intracellular subsistence. However, the molecular underpinnings of how the parasite gains resources...
12.
Bartolini D, Stabile A, Bastianelli S, Giustarini D, Pierucci S, Busti C, et al.
Redox Biol
. 2021 Jun;
45:102041.
PMID: 34146958
Viral infections sustain their replication cycle promoting a pro-oxidant environment in the host cell. In this context, specific alterations of the levels and homeostatic function of the tripeptide glutathione have...
13.
Smith D, Kannan G, Coppens I, Wang F, Mai Nguyen H, Cerutti A, et al.
Elife
. 2021 Apr;
10.
PMID: 33904393
Many of the world's warm-blooded species are chronically infected with tissue cysts, including an estimated one-third of the global human population. The cellular processes that permit long-term persistence within the...
14.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
15.
McDonald C, Smith D, Di Cristina M, Kannan G, Dou Z, Carruthers V
mSphere
. 2020 Feb;
5(1).
PMID: 32051238
The lysosome-like vacuolar compartment (VAC) is a major site of proteolysis in the intracellular parasite Previous studies have shown that genetic ablation of a VAC-residing cysteine protease, cathepsin protease L...
16.
Mayoral J, Di Cristina M, Carruthers V, Weiss L
Methods Mol Biol
. 2019 Nov;
2071:269-282.
PMID: 31758458
Toxoplasma gondii, a member of the Apicomplexa, is known for its ability to infect an impressive range of host species. It is a common human infection that causes significant morbidity...
17.
Piro F, Carruthers V, Di Cristina M
Methods Mol Biol
. 2019 Nov;
2071:117-123.
PMID: 31758449
Toxoplasma gondii has become a model for studying the phylum Apicomplexa, and more in general parasite-host interactions, thanks to its ease of growth in culture and availability of a broad...
18.
Role of Chloroquine Resistance Transporter in Bradyzoite Viability and Digestive Vacuole Maintenance
Kannan G, Di Cristina M, Schultz A, Huynh M, Wang F, Schultz T, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31387907
is a ubiquitous pathogen that can cause encephalitis, congenital defects, and ocular disease. has also been implicated as a risk factor for mental illness in humans. The parasite persists in...
19.
Thornton L, Teehan P, Floyd K, Cochrane C, Bergmann A, Riegel B, et al.
PLoS Pathog
. 2019 Jun;
15(6):e1007775.
PMID: 31170269
Toxoplasma gondii is an apicomplexan parasite with the ability to use foodborne, zoonotic, and congenital routes of transmission that causes severe disease in immunocompromised patients. The parasites harbor a lysosome-like...
20.
Di Cristina M, Carruthers V
Parasitology
. 2018 Feb;
145(9):1119-1126.
PMID: 29463318
Although the application of CRISPR/Cas9 genome engineering approaches was first reported in apicomplexan parasites only 3 years ago, this technology has rapidly become an essential component of research on apicomplexan...