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Manisha Brahmachary

Explore the profile of Manisha Brahmachary including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1590
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Recent Articles
11.
Wong E, Xu C, Brahmachary M, Xu P
PLoS One . 2016 May; 11(5):e0154984. PMID: 27171474
Mouse N-ethyl-N-nitrosourea (ENU) mutagenesis has generated many useful animal models for human diseases. Here we describe the identification of a novel ENU-induced mouse mutant strain Turner (Tur) that displays circling...
12.
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, et al.
Immunity . 2015 Jun; 42(6):1143-58. PMID: 26070485
Tissue effector cells of the monocyte lineage can differentiate into different cell types with specific cell function depending on their environment. The phenotype, developmental requirements, and functional mechanisms of immune...
13.
Brahmachary M, Guilmatre A, Quilez J, Hasson D, Borel C, Warburton P, et al.
PLoS Genet . 2014 Jun; 10(6):e1004418. PMID: 24945355
Tandem repeats are common in eukaryotic genomes, but due to difficulties in assaying them remain poorly studied. Here, we demonstrate the utility of Nanostring technology as a targeted approach to...
14.
Bala Tannan N, Brahmachary M, Garg P, Borel C, Alnefaie R, Watson C, et al.
Hum Mol Genet . 2013 Nov; 23(5):1224-36. PMID: 24186870
X chromosome inactivation (XCI) is an epigenetic mechanism that silences the majority of genes on one X chromosome in females. Previous studies have suggested that the spread of XCI might...
15.
Basso K, Mussolin L, Lettieri A, Brahmachary M, Lim W, Califano A, et al.
Genes Chromosomes Cancer . 2011 Oct; 50(12):1063-75. PMID: 21987448
T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) share common morphological and immunophenotypic features and are treated with similar therapeutic approaches. Nonetheless, they show distinct clinical presentations, suggesting that they...
16.
Sharp A, Stathaki E, Migliavacca E, Brahmachary M, Montgomery S, Dupre Y, et al.
Genome Res . 2011 Aug; 21(10):1592-600. PMID: 21862626
X-chromosome inactivation (XCI) is a dosage compensation mechanism that silences the majority of genes on one X chromosome in each female cell. To characterize epigenetic changes that accompany this process,...
17.
Mandelbaum J, Bhagat G, Tang H, Mo T, Brahmachary M, Shen Q, et al.
Cancer Cell . 2010 Dec; 18(6):568-79. PMID: 21156281
Diffuse large B cell lymphoma (DLBCL) is a heterogeneous disease composed of at least two distinct subtypes: germinal center B cell-like (GCB) and activated B cell-like (ABC) DLBCL. These phenotypic...
18.
Zhao X, D Arca D, Lim W, Brahmachary M, Carro M, Ludwig T, et al.
Dev Cell . 2009 Aug; 17(2):210-21. PMID: 19686682
Self-renewal and proliferation of neural stem cells and the decision to initiate neurogenesis are crucial events directing brain development. Here we show that the ubiquitin ligase Huwe1 operates upstream of...
19.
Compagno M, Lim W, Grunn A, Nandula S, Brahmachary M, Shen Q, et al.
Nature . 2009 May; 459(7247):717-21. PMID: 19412164
Diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma in adulthood, comprises multiple biologically and clinically distinct subtypes including germinal centre B-cell-like (GCB) and activated B-cell-like (ABC) DLBCL....
20.
Brahmachary M, Schonbach C, Yang L, Huang E, Tan S, Chowdhary R, et al.
BMC Bioinformatics . 2007 Jan; 7 Suppl 5:S8. PMID: 17254313
Background: Mammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition receptors and other proteins affect the expression...