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Manas Pratim Chakraborty

Explore the profile of Manas Pratim Chakraborty including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 13
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Recent Articles
1.
Chowdhury S, Chakraborty M, Roy S, Dey B, Gangopadhyay K, Das R
J Biol Chem . 2024 Jul; 300(8):107535. PMID: 38971313
Bruton's tyrosine kinase (BTK) regulates diverse cellular signaling of the innate and adaptive immune system in response to microbial pathogens. Downregulation or constitutive activation of BTK is reported in patients...
2.
Chakraborty A, Ghosh S, Chakraborty M, Mukherjee S, Roy S, Das R, et al.
J Med Chem . 2024 Mar; 67(7):5902-5923. PMID: 38520399
Nuclear factor kappa beta (NF-κB) plays a pivotal role in breast cancer, particularly triple-negative breast cancer, by promoting inflammation, proliferation, epithelial-mesenchymal transition, metastasis, and drug resistance. Upregulation of NF-κB boosts...
3.
Chakraborty M, Das D, Mondal P, Kaul P, Bhattacharyya S, Das P, et al.
Nat Commun . 2024 Feb; 15(1):1346. PMID: 38355851
Ligand-independent activation of VEGFRs is a hallmark of diabetes and several cancers. Like EGFR, VEGFR2 is activated spontaneously at high receptor concentrations. VEGFR1, on the other hand, remains constitutively inactive...
4.
Chatterjee A, Ruturaj , Chakraborty M, Nandi S, Purkayastha P
Anal Bioanal Chem . 2022 Jun; 414(20):6055-6067. PMID: 35697813
Lateral heterogeneity in cell membranes features a variety of compositions that influence their inherent properties. One such biophysical variation is the formation of a membrane or lipid raft, which plays...
5.
Chakraborty A, Roy S, Chakraborty M, Roy S, Purkait K, Koley T, et al.
Inorg Chem . 2021 Nov; 60(23):18379-18394. PMID: 34780170
Eight new ruthenium(II) complexes of ,-chelating pyrazolylbenzimidazole ligands of the general formula [Ru(-cym)(L)X] [where the ligand L is 2-(1-pyrazol-1-yl)-1-benzo[]imidazole () substituted at the 4 position of the pyrazole ring by...
6.
Maji M, Bhattacharya I, Acharya S, Chakraborty M, Gupta A, Mukherjee A
Inorg Chem . 2021 Mar; 60(7):4342-4346. PMID: 33711231
Platinum(IV) complexes of orotic acid selectively target liver cancer cells displaying enhanced activity and higher uptake in Hep G2. The comparatively higher expression of Organic Anion Transporter 2 (OAT2) in...
7.
Chakraborty M, Bhattacharyya S, Roy S, Bhattacharya I, Das R, Mukherjee A
J Biol Chem . 2021 Feb; 296:100449. PMID: 33617879
Hck, a Src family nonreceptor tyrosine kinase (SFK), has recently been established as an attractive pharmacological target to improve pulmonary function in COVID-19 patients. Hck inhibitors are also well known...
8.
Acharya S, Maji M, Chakraborty M, Bhattacharya I, Das R, Gupta A, et al.
Inorg Chem . 2021 Feb; 60(5):3418-3430. PMID: 33554592
Platinum-based complexes are one of the most successful chemotherapeutic agents having a significant ground in cancer chemotherapy despite their side effects. During the past few decades, Ru(II) complexes have been...