Manabu Taura
Overview
Explore the profile of Manabu Taura including associated specialties, affiliations and a list of published articles.
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36
Citations
1636
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Recent Articles
1.
Matsui Y, Takemura N, Shirasaki Y, Takahama M, Noguchi Y, Ikoma K, et al.
Int Immunol
. 2022 Jun;
34(10):505-518.
PMID: 35759801
Nod-like receptor family pyrin domain-containing 3 (NLRP3) is a cytosolic innate immune receptor that senses organelle dysfunction induced by various stimuli, such as infectious, environmental, metabolic and drug stresses. Upon...
2.
Ikoma K, Takahama M, Kimishima A, Pan Y, Taura M, Nakayama A, et al.
Int Immunol
. 2022 May;
34(10):493-504.
PMID: 35639943
The human body is exposed to various particulates of industrial, environmental, or endogenous origin. Invading or intrinsic particulates can induce inflammation by aberrantly activating the immune system, thereby causing crystallopathies....
3.
Taura M, Frank J, Takahashi T, Kong Y, Kudo E, Song E, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(20):e2011665119.
PMID: 35549556
APOBEC3A (A3A) is a cytidine deaminase that inactivates a variety of viruses through introduction of lethal mutations to the viral genome. Additionally, A3A can suppress HIV-1 transcription in a deaminase-independent...
4.
Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH
Maeda H, Ishima Y, Saruwatari J, Mizuta Y, Minayoshi Y, Ichimizu S, et al.
J Control Release
. 2021 Dec;
341:457-474.
PMID: 34856227
Kupffer cells are a key source of reactive oxygen species (ROS) and are implicated in the development of steatohepatitis and fibrosis in nonalcoholic steatohepatitis (NASH). We recently developed a polythiolated...
5.
Wyllie A, Fournier J, Casanovas-Massana A, Campbell M, Tokuyama M, Vijayakumar P, et al.
N Engl J Med
. 2020 Aug;
383(13):1283-1286.
PMID: 32857487
No abstract available.
6.
Vogels C, Brito A, Wyllie A, Fauver J, Ott I, Kalinich C, et al.
Nat Microbiol
. 2020 Jul;
5(10):1299-1305.
PMID: 32651556
The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exemplifies the critical need for accurate and rapid diagnostic assays to prompt clinical and public health interventions. Currently, several...
7.
Murakami H, Suzuki T, Tsuchiya K, Gatanaga H, Taura M, Kudo E, et al.
Viruses
. 2020 Mar;
12(3).
PMID: 32210193
Current therapies for human immunodeficiency virus type 1 (HIV-1) do not completely eliminate viral reservoirs in cells, such as macrophages. The HIV-1 accessory protein viral protein R (Vpr) promotes virus...
8.
The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV
Treger R, Pope S, Kong Y, Tokuyama M, Taura M, Iwasaki A
Immunity
. 2019 Feb;
50(2):334-347.e9.
PMID: 30709743
Elevated endogenous retrovirus (ERV) transcription and anti-ERV antibody reactivity are implicated in lupus pathogenesis. Overproduction of non-ecotropic ERV (NEERV) envelope glycoprotein gp70 and resultant nephritis occur in lupus-prone mice, but...
9.
Taura M, Song E, Ho Y, Iwasaki A
Proc Natl Acad Sci U S A
. 2019 Jan;
116(6):2282-2289.
PMID: 30670656
HIV-1 integrates into the genome of target cells and establishes latency indefinitely. Understanding the molecular mechanism of HIV-1 latency maintenance is needed for therapeutic strategies to combat existing infection. In...
10.
Hayashi K, Taura M, Iwasaki A
Sci Signal
. 2018 May;
11(528).
PMID: 29717061
Toll-like receptor 9 (TLR9) recognizes DNA in endosomes and activates distinct signaling pathways to stimulate the production of proinflammatory cytokines and type I interferons (IFNs). The assembly of signaling platforms...