Man-Ru Wu
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Explore the profile of Man-Ru Wu including associated specialties, affiliations and a list of published articles.
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12
Citations
88
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Recent Articles
1.
Costa E, Chen J, Guldner I, Mboning L, Schmahl N, Tsenter A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975269
Aging is associated with progressive tissue dysfunction, leading to frailty and mortality. Characterizing aging features, such as changes in gene expression and dynamics, shared across tissues or specific to each...
2.
Lin C, Wu M, Tanasa B, Prakhar P, Deng B, Davis A, et al.
Diabetes
. 2024 Oct;
74(1):96-107.
PMID: 39446557
Article Highlights:
3.
Xie Z, Zhang T, Kim S, Lu J, Zhang W, Lin C, et al.
PLoS Genet
. 2024 May;
20(5):e1011273.
PMID: 38728357
Existing imaging genetics studies have been mostly limited in scope by using imaging-derived phenotypes defined by human experts. Here, leveraging new breakthroughs in self-supervised deep representation learning, we propose a...
4.
Li L, Sun Y, Davis A, Shah S, Hamed L, Wu M, et al.
Cell Rep
. 2023 Jun;
42(6):112596.
PMID: 37269288
Neural progenitor cells lengthen their cell cycle to prime themselves for differentiation as development proceeds. It is currently not clear how they counter this lengthening and avoid being halted in...
5.
Lin C, Sun Y, Chan C, Wu M, Gu L, Davis A, et al.
J Biol Chem
. 2022 Feb;
298(4):101674.
PMID: 35148987
Adeno-associated viruses (AAVs) targeting specific cell types are powerful tools for studying distinct cell types in the central nervous system (CNS). Cis-regulatory modules (CRMs), e.g., enhancers, are highly cell-type-specific and...
6.
Lin C, Sun Y, Lee S, Mujica E, Kunchur C, Wu M, et al.
STAR Protoc
. 2022 Feb;
3(1):101143.
PMID: 35141566
Ocular drug implants (ODIs) are beneficial for treating ocular diseases. However, the lack of a robust injection approach for small-eyed model organisms has been a major technical limitation in developing...
7.
Sun Y, Lin C, Wu M, Lee S, Yang J, Kunchur C, et al.
Cell Rep Methods
. 2022 Feb;
1(8).
PMID: 35128514
Using small molecule drugs to treat eye diseases carries benefits of specificity, scalability, and transportability, but their efficacy is significantly limited by a fast intraocular clearance rate. Ocular drug implants...
8.
Chan C, Lonfat N, Zhao R, Davis A, Li L, Wu M, et al.
Development
. 2020 Jul;
147(14).
PMID: 32631829
Transcription factors (TFs) are often used repeatedly during development and homeostasis to control distinct processes in the same and/or different cellular contexts. Considering the limited number of TFs in the...
9.
Lin C, Wu M, Huang W, Chow D, Hsiao G, Cheng Y
Int J Mol Sci
. 2019 Apr;
20(7).
PMID: 30979028
N-retinylidene-N-retinylethanolamine (A2E) and other bisretinoids are components of lipofuscin and accumulate in retinal pigment epithelial (RPE) cells-these adducts are recognized in the pathogenesis of retinal degeneration. Further, blue light-emitting diode...
10.
Wu M, Lin C, Ho J, Hsiao G, Cheng Y
Cell Physiol Biochem
. 2018 Nov;
51(1):63-79.
PMID: 30439705
Background/aims: Blue light-emitting diode light (BLL)-induced phototoxicity plays an important role in ocular diseases and causes retinal degeneration and apoptosis in human retinal pigment epithelial (RPE) cells. Cistanche tubulosa extract...