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Mamta Dadwal

Explore the profile of Mamta Dadwal including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 31
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Recent Articles
1.
Dadwal M, Kang C, Song H, Sun X, Dai A, Baidoo K, et al.
Bioorg Med Chem Lett . 2011 Nov; 21(24):7513-5. PMID: 22047687
A new bifunctional ligand C-DEPA was designed and synthesized as a component for antibody-targeted radiation therapy (radioimmunotherapy, RIT) of cancer. C-DEPA was conjugated to a tumor targeting antibody, trastuzumab, and...
2.
Chong H, Song H, Kang C, Le T, Sun X, Dadwal M, et al.
Chem Commun (Camb) . 2011 Apr; 47(19):5584-6. PMID: 21468393
A novel bifunctional ligand (3p-C-NETA) for antibody-targeted radioimmunotherapy (RIT) of β-emitting radioisotopes (90)Y and (177)Lu was efficiently synthesized via an unexpected regiospecific ring opening of an aziridinium ion. 3p-C-NETA instantly...
3.
Shanbhag P, Nareddy P, Dadwal M, Mobin S, Namboothiri I
Org Biomol Chem . 2010 Aug; 8(21):4867-73. PMID: 20734004
Reaction of nitroalkenes or nitrodienes with methyl vinyl ketone (MVK) or acrylate in the presence of the imidazole-LiCl catalyst system provides Rauhut-Currier (vinylogous Morita-Baylis-Hillman) adducts in moderate yield. Under similar...
4.
Chong H, Song H, Dadwal M, Sun X, Sin I, Chen Y
J Org Chem . 2009 Dec; 75(1):219-21. PMID: 19954140
Various aziridinium salts were efficiently prepared from bromination of a series of backbone substituted N,N-bisubstituted beta-amino alcohols and isolated via flash column chromatography. The effect of C-substitution, N-substitution, solvent, leaving...
5.
Song H, Dadwal M, Lee Y, Mick E, Chong H
Angew Chem Int Ed Engl . 2009 Jan; 48(7):1328-30. PMID: 19142922
Rock trapping and exploration: Aziridinium bromide salts were discovered serendipitously during bromination of N,N-dicarboxymethylated beta-amino alcohols. Regiospecific ring-opening and rearrangement of the isolated, surprisingly stable aziridinium salts produces useful molecules...
6.
Dadwal M, Mobin S, Namboothiri I
Org Biomol Chem . 2006 Jun; 4(13):2525-8. PMID: 16791313
Novel alpha-hydrazino-alpha,beta-unsaturated nitroalkenes, which exhibit dynamic phenomenon on the NMR time scale, were synthesized in excellent yields via imidazole or DMAP mediated Morita-Baylis-Hillman (MBH) type reaction of nitroalkenes with azodicarboxylates.
7.
Deb I, Dadwal M, Mobin S, Namboothiri I
Org Lett . 2006 Mar; 8(6):1201-4. PMID: 16524303
[reaction: see text] The Morita-Baylis-Hillman reaction of a variety of conjugated nitroalkenes with activated nonenolizable carbonyl compounds such as glyoxylate, trifluoropyruvate, pyruvaldehyde, and ninhydrin in the presence of 40-100 mol...
8.
Dadwal M, Mohan R, Panda D, Mobin S, Namboothiri I
Chem Commun (Camb) . 2006 Jan; (3):338-40. PMID: 16391753
The Morita-Baylis-Hillman (MBH) adducts of beta-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit...