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Maki Tsujita

Explore the profile of Maki Tsujita including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 318
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Recent Articles
1.
Tsujita M, Melchior J, Yokoyama S
Arterioscler Thromb Vasc Biol . 2024 Mar; 44(5):1042-1052. PMID: 38545782
The brain is the most lipid-rich organ in the body, and the intricate interplay between lipid metabolism and pathologies associated with neurodegenerative disorders is being increasingly recognized. The brain is...
2.
Castleberry M, Raby C, Ifrim A, Shibata Y, Matsushita S, Ugawa S, et al.
J Lipid Res . 2023 Jan; 64(2):100328. PMID: 36626966
HDL are dynamic transporters of diverse molecular cargo and play critical roles in lipid metabolism and inflammation. We have previously reported that HDL transport both host and nonhost small RNAs...
3.
Otsuji S, Nishio Y, Tsujita M, Rio M, Huber C, Anton-Plagaro C, et al.
J Med Genet . 2022 Sep; 60(4):359-367. PMID: 36113987
Purpose: The Retriever subunit is the third responsible gene for Ritscher-Schinzel syndrome (RSS) after and . To date, only one pair of siblings have been reported and their condition was...
4.
Tsujita M, Vaisman B, Chengyu L, Vickers K, Okuhira K, Braesch-Andersen S, et al.
FEBS Lett . 2020 Oct; 595(6):773-788. PMID: 33020907
Apolipoprotein (apo) A-I, the major structural protein of high-density lipoprotein (HDL), is present in human and mouse cerebrospinal fluid (CSF) despite its lack of expression in brain cells. To identify...
5.
Kitano V, Ohyama Y, Hayashida C, Ito J, Okayasu M, Sato T, et al.
J Cell Sci . 2020 Apr; 133(10). PMID: 32295848
Osteoporosis is associated with vessel diseases attributed to hyperlipidemia, and bone resorption by multinucleated osteoclasts is related to lipid metabolism. In this study, we generated low-density lipoprotein receptor ()/lectin-like oxidized...
6.
Tsujita M, Akita N, Yokota T, Kobayashi F, Yokoyama S
J Atheroscler Thromb . 2019 May; 27(1):25-37. PMID: 31092744
Aim: Probucol is a controversial drug to inhibit ATP-binding cassette transporter A1 (ABCA1) and to exhibit some positive clinical effects such as regression of xanthomas. It reportedly rescues female infertility...
7.
Tsujita M, Wolska A, Gutmann D, Remaley A
Curr Atheroscler Rep . 2018 Nov; 20(12):59. PMID: 30397748
Purpose Of Review: Summarize the initial discovery of discoidal high-density lipoprotein (HDL) in human plasma and review more recent innovations that span the use of reconstituted nanodisc HDL for membrane...
8.
Fuentes L, Beck W, Tsujita M, Weers P
Biochemistry . 2018 Mar; 57(15):2200-2210. PMID: 29578333
Charged residues of the C-terminal domain of human apolipoprotein A-I (apoA-I) were targeted by site-directed mutagenesis. A series of mutant proteins was engineered in which lysine residues (Lys 195, 206,...
9.
Tsujita M, Hossain M, Lu R, Tsuboi T, Okumura-Noji K, Yokoyama S
J Atheroscler Thromb . 2017 Apr; 24(11):1132-1149. PMID: 28428480
Aim: To study atherosclerosis risk in diabetes, we investigated ATP-binding cassette transporter A1 (ABCA1) expression and high-density lipoprotein (HDL) biogenesis in the liver and hepatocytes under hyperglycemic conditions. Methods And...
10.
Sano O, Tsujita M, Shimizu Y, Kato R, Kobayashi A, Kioka N, et al.
PLoS One . 2016 May; 11(5):e0155400. PMID: 27196068
ATP-binding cassette G1 (ABCG1) and ABCG4, expressed in neurons and glia in the central nervous system, mediate cholesterol efflux to lipid acceptors. The relationship between cholesterol level in the central...