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Majid Nikpay

Explore the profile of Majid Nikpay including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 3086
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Recent Articles
1.
Soubeyrand S, Lau P, Nikpay M, Ma L, Bjorkegren J, McPherson R
Circ Genom Precis Med . 2024 Dec; 17(6):e004674. PMID: 39624902
Background: Genome-wide association studies identified a 20-Kb region of chromosome 8 (8q24.13) associated with plasma lipids, hepatic steatosis, and risk for coronary artery disease. The region is proximal to ,...
2.
Nikpay M
Epigenomes . 2024 Aug; 8(3). PMID: 39189255
An understanding of the molecular mechanism whereby an environmental chemical causes a disease is important for the purposes of future applications. In this study, a multiomics workflow was designed to...
3.
Nikpay M
Epigenomes . 2023 Sep; 7(3). PMID: 37754271
Understanding the epigenome paths through which smoking contributes to cardiometabolic traits is important for downstream applications. In this study, an SNP-based analytical pipeline was used to integrate several publicly available...
4.
Nikpay M
Front Genet . 2023 Jun; 14:1093882. PMID: 37274792
Identifying DNA methylation sites that regulate the metabolome is important for several purposes. In this study, publicly available GWAS data were integrated to find methylation sites that impact metabolome through...
5.
Nikpay M, Ravati S, McPherson R
Epigenomics . 2022 Jul; PMID: 35852134
Identifying DNA methylation sites that regulate the blood proteome is important for biomedical purposes. Here the authors performed a genome-wide search to find DNA methylation sites that impact proteins.  The...
6.
Chi X, Bielawska B, Nikpay M, Dent R
Can J Diabetes . 2022 May; 46(3):233-237. PMID: 35568423
Objectives: Our aim in this study was to compare the change in waist circumference given the same degree of weight loss in patients who meet the criteria for metabolic syndrome...
7.
Dam V, Onland-Moret N, Burgess S, Chirlaque M, Peters S, Schuit E, et al.
J Clin Endocrinol Metab . 2022 Mar; 107(7):e2952-e2961. PMID: 35306566
Background: Accelerated reproductive aging, in women indicated by early natural menopause, is associated with increased coronary heart disease (CHD) risk in observational studies. Conversely, an adverse CHD risk profile has...
8.
Soubeyrand S, Lau P, Nikpay M, Dang A, McPherson R
Circ Genom Precis Med . 2022 Feb; 15(2):e003428. PMID: 35130031
Background: Fibronectin () is an essential regulator of homodynamic processes and tissue remodeling that have been proposed to contribute to atherosclerosis. Moreover, recent large-scale genome-wide association studies (GWAS) have linked...
9.
Nikpay M, Ravati S, Dent R, McPherson R
Nutrients . 2021 Jul; 13(6). PMID: 34207686
Here, we performed a genome-wide search for methylation sites that contribute to the risk of obesity. We integrated methylation quantitative trait locus (mQTL) data with BMI GWAS information through a...
10.
Beehler K, Nikpay M, Lau P, Dang A, Lagace T, Soubeyrand S, et al.
Arterioscler Thromb Vasc Biol . 2021 Jun; 41(8):2252-2262. PMID: 34134519
OBJECTIVE: Leveraging microRNA-Seq data and the 1000 Genomes imputed genotypes, we identified rs174561 as a strong microRNA quantitative trait loci for circulating microRNA-1908-5p with higher miR-1908-5p and reduced LDL (lowdensity...