Maja Przybylowska
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Explore the profile of Maja Przybylowska including associated specialties, affiliations and a list of published articles.
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6
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61
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Recent Articles
1.
Przybylowska M, Dzierzbicka K, Kowalski S, Demkowicz S, Dasko M, Inkielewicz-Stepniak I
J Enzyme Inhib Med Chem
. 2022 Apr;
37(1):1012-1022.
PMID: 35361039
In this work, we designed, synthesised and biologically investigated a novel series of 14 - and -phosphorylated tacrine derivatives as potential anti-Alzheimer's disease agents. In the reaction of 9-chlorotacrine and...
2.
Przybylowska M, Dzierzbicka K, Kowalski S, Chmielewska K, Inkielewicz-Stepniak I
Curr Neuropharmacol
. 2020 Dec;
19(8):1323-1344.
PMID: 33342413
The aim of this work is to review tacrine analogues from the last three years, which were not included in the latest review work, donepezil and galantamine hybrids from 2015...
3.
Chmielewska K, Dzierzbicka K, Inkielewicz-Stepniak I, Przybylowska M
Chem Res Toxicol
. 2020 Mar;
33(7):1561-1578.
PMID: 32202758
Despite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around the world. The resistance of cancer cells...
4.
Przybylowska M, Inkielewicz-Stepniak I, Kowalski S, Dzierzbicka K, Demkowicz S, Dasko M
Med Chem
. 2019 Jul;
16(7):947-957.
PMID: 31309898
Background: Alzheimer's disease (AD) is progressive and irreversible neurodegenerative disorder. Current pharmacotherapy is not able to stop progression of the disease and can only improve cognitive functions. Therefore, new drugs...
5.
Przybylowska M, Kowalski S, Dzierzbicka K, Inkielewicz-Stepniak I
Curr Neuropharmacol
. 2018 Apr;
17(5):472-490.
PMID: 29651948
Tacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model...
6.
Dasko M, Przybylowska M, Rachon J, Maslyk M, Kubinski K, Misiak M, et al.
Eur J Med Chem
. 2017 Feb;
128:79-87.
PMID: 28152429
In the present work, we report convenient methods for the synthesis of 3-(4-aminophenyl)-coumarin-7-O-sulfamate derivatives N-acylated with fluorinated analogues of benzoic or phenylacetic acid as steroid sulfatase (STS) inhibitors. The design...