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Maik Huttemann

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Articles 134
Citations 4459
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Recent Articles
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Fogo G, Raghunayakula S, Emaus K, Torres Torres F, Shangguan G, Wider J, et al.
Autophagy . 2025 Feb; PMID: 40016670
Mitochondrial damage and dysfunction are hallmarks of neuronal injury during cerebral ischemia-reperfusion (I/R). Critical mitochondrial functions including energy production and cell signaling are perturbed during I/R, often exacerbating damage and...
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Morse P, Pasupathi V, Vuljaj S, Yazdi N, Zurek M, Wan J, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39941082
It was previously reported that tyrosine 97 (Y97) of cytochrome is phosphorylated in cow heart tissue under physiological conditions. Y97 phosphorylation was shown to partially inhibit respiration in vitro in...
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Carter J, Su Y, Al-Antary E, Zhao J, Qiao X, Wang G, et al.
J Exp Clin Cancer Res . 2025 Jan; 44(1):10. PMID: 39780285
Background: Venetoclax + azacitidine is a frontline treatment for older adult acute myeloid leukemia (AML) patients and a salvage therapy for relapsed/refractory patients who have been treated with intensive chemotherapy....
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Akter S, Akter S, Tuli M, Eisenberg D, Lotvola A, Islam H, et al.
Comput Biol Med . 2024 Nov; 184:109413. PMID: 39615231
The rising incidences of myocardial infarction (MI), often affecting individuals without traditional risk factors, highlight the urgent need for improved early detection using personal health data. However, health surveys and...
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Pham L, Arroum T, Wan J, Pavelich L, Bell J, Morse P, et al.
Redox Biol . 2024 Nov; 78():103426. PMID: 39566165
Mitochondria are essential to cellular function as they generate the majority of cellular ATP, mediated through oxidative phosphorylation, which couples proton pumping of the electron transport chain (ETC) to ATP...
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Yanagisawa S, Kamei T, Shimada A, Gladyck S, Aras S, Huttemann M, et al.
J Inorg Biochem . 2024 Aug; 260:112673. PMID: 39094247
Cytochrome c oxidase (CcO) reduces O, pumps protons in the mitochondrial respiratory chain, and is essential for oxygen consumption in the cell. The coiled-coil-helix-coiled-coil-helix domain-containing 2 (CHCHD2; also known as...
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Wu S, Liu F, Gai Y, Carter J, Edwards H, Huttemann M, et al.
Leuk Res . 2024 Jul; 144:107547. PMID: 38968731
FMS-like tyrosine kinase 3 (FLT3) mutations occur in approximately one third of acute myeloid leukemia (AML) patients. FLT3-Internal tandem duplication (FLT3-ITD) mutations are the most common FLT3 mutations and are...
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Morse P, Wan J, Arroum T, Herroon M, Kalpage H, Bazylianska V, et al.
Biomolecules . 2024 Jun; 14(6). PMID: 38927098
Cytochrome (Cyt) is important for both mitochondrial respiration and apoptosis, both of which are altered in cancer cells that switch to Warburg metabolism and manage to evade apoptosis. We earlier...
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Arroum T, Hish G, Burghardt K, Ghamloush M, Bazzi B, Mrech A, et al.
J Strength Cond Res . 2024 Jun; 38(7):1189-1199. PMID: 38900170
Arroum, T, Hish, GA, Burghardt, KJ, Ghamloush, M, Bazzi, B, Mrech, A, Morse, PT, Britton, SL, Koch, LG, McCully, JD, Hüttemann, M, and Malek, MH. Mitochondria transplantation: Rescuing innate muscle...