Mahmoud S Alghamri
Overview
Explore the profile of Mahmoud S Alghamri including associated specialties, affiliations and a list of published articles.
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29
Citations
686
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Recent Articles
1.
Nunez F, Banerjee K, Mujeeb A, Mauser A, Tronrud C, Zhu Z, et al.
bioRxiv
. 2024 Apr;
PMID: 38559270
One Sentence Summary: The inhibition of autophagy sensitizes mIDH1 glioma cells to radiation, thus creating a promising therapeutic strategy for mIDH1 glioma patients. Graphical Abstract: Our genetically engineered mIDH1 mouse...
2.
Excoffon K, Avila C, Alghamri M, Kolawole A
Biol Cell
. 2023 Oct;
115(11):e202300901.
PMID: 37807768
No abstract available.
3.
Garcia-Fabiani M, Haase S, Banerjee K, McClellan B, Zhu Z, McClellan B, et al.
bioRxiv
. 2023 Jul;
PMID: 37398299
Statement Of Significance: This study uncovers the role of the H3.3-G34 mutation in reprogramming the tumor immune microenvironment in diffuse hemispheric gliomas. Our findings support the implementation of precision medicine...
4.
Dmello C, Zhao J, Chen L, Gould A, Castro B, Arrieta V, et al.
Nat Commun
. 2023 Mar;
14(1):1566.
PMID: 36949040
Whereas the contribution of tumor microenvironment to the profound immune suppression of glioblastoma (GBM) is clear, tumor-cell intrinsic mechanisms that regulate resistance to CD8 T cell mediated killing are less...
5.
McClellan B, Haase S, Nunez F, Alghamri M, Dabaja A, Lowenstein P, et al.
J Clin Invest
. 2023 Jan;
133(2).
PMID: 36647827
Epigenetic remodeling is a molecular hallmark of gliomas, and it has been identified as a key mediator of glioma progression. Epigenetic dysregulation contributes to gliomagenesis, tumor progression, and responses to...
6.
Haase S, Banerjee K, Mujeeb A, Hartlage C, Nunez F, Nunez F, et al.
J Clin Invest
. 2022 Sep;
132(22).
PMID: 36125896
Pediatric high-grade gliomas (pHGGs) are the leading cause of cancer-related deaths in children in the USA. Sixteen percent of hemispheric pediatric and young adult HGGs encode Gly34Arg/Val substitutions in the...
7.
McClellan B, Alghamri M, Thalla R, Lowenstein P, Castro M
STAR Protoc
. 2022 May;
3(2):101357.
PMID: 35634359
Here, we present a mass cytometry protocol optimized to examine the phenotype of immune cells within the mouse glioma microenvironment, using a Sleeping Beauty transposon-mediated mouse glioma model. We describe...
8.
Alghamri M, Banerjee K, Mujeeb A, Mauser A, Taher A, Thalla R, et al.
ACS Nano
. 2022 May;
16(6):8729-8750.
PMID: 35616289
Glioblastoma (GBM) is an aggressive primary brain cancer, with a 5 year survival of ∼5%. Challenges that hamper GBM therapeutic efficacy include (i) tumor heterogeneity, (ii) treatment resistance, (iii) immunosuppressive...
9.
Excoffon K, Avila C, Alghamri M, Kolawole A
Biol Cell
. 2022 Apr;
114(7):185-198.
PMID: 35389514
MAGI-1 is a critical cellular scaffolding protein with over 110 different cellular and microbial protein interactors. Since the discovery of MAGI-1 in 1997, MAGI-1 has been implicated in diverse cellular...
10.
Cordell E, Alghamri M, Castro M, Gutmann D
Neuro Oncol
. 2022 Mar;
24(10):1647-1657.
PMID: 35325210
The brain tumor microenvironment contains numerous distinct types of nonneoplastic cells, which each serve a diverse set of roles relevant to the formation, maintenance, and progression of these central nervous...