Mahmoud M Sheha
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Explore the profile of Mahmoud M Sheha including associated specialties, affiliations and a list of published articles.
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6
Citations
15
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Recent Articles
1.
Maghraby M, Almutairi T, Brase S, Salem O, Youssif B, Sheha M
Molecules
. 2023 Oct;
28(20).
PMID: 37894571
A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a-i was designed and synthesized as antiproliferative agents targeting aromatase enzymes. The antiproliferative activity of the new hybrids against four cancer...
2.
Maghraby M, Salem O, Youssif B, Sheha M
Chem Biol Drug Des
. 2022 Nov;
101(3):749-759.
PMID: 36366966
A novel series of 1,2,3-triazole/chalcone hybrids 6a-n was designed and synthesized using a molecular hybridization approach to develop a new cytotoxic agent capable of targeting epidermal growth factor receptor (EGFR)...
3.
Mohamed N, Sheha M, Hassan H, Abdel-Hafez L, Omar F
Bioorg Chem
. 2018 Sep;
81:599-611.
PMID: 30248511
Four series of triazolylnaphthyridinone derivatives were synthesized as structural surrogates of nalidixic acid. The targeted derivatives involve: 3-(5-acylamino-2H-1,2,4-triazol-3-yl)-naphtyridin-4-ones 6(a-e); 3-(5-benzylidineamino-2H-1,2,4-triazol-3-yl)-naphthyridin-4-ones 8(a-g) and their 6-bromonaphthyridin-4-one analogs 7(a-e); 9(a-g). The synthesized compounds...
4.
Hamdy A, Sheha M, Abdel-Hafez A, Shouman S
Int J Med Chem
. 2018 Jan;
2017:7386125.
PMID: 29362676
Griseofulvin is an important antifungal agent that has recently received attention due to its antiproliferative activity in mammalian cancer cells. Study of SAR of some griseofulvin analogues has led to...
5.
Khedr A, Sheha M, Darwish I
J Chromatogr B Analyt Technol Biomed Life Sci
. 2007 Jul;
856(1-2):337-42.
PMID: 17644495
A high-performance liquid chromatographic method for the determination of trimetazidine dihydrochloride (TMZ) in spiked human plasma is described. The method is based on the pre-column derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl)...
6.
Sheha M, El-Koussi N, Farag H
Arch Pharm (Weinheim)
. 2003 Apr;
336(1):47-52.
PMID: 12666253
To overcome the problems of peptidomimetic drug delivery to the specific organs, the use of dihydropyridine <--> pyridinium chemical delivery systems to deliver peptides to the brain is considered in...