Magdalena Juhaszova
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Explore the profile of Magdalena Juhaszova including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Maltsev A, Ventura Subirachs V, Monfredi O, Juhaszova M, Ajay Warrier P, Rakshit S, et al.
Cells
. 2024 Nov;
13(22).
PMID: 39594633
The rate of spontaneous action potentials (APs) generated by sinoatrial node cells (SANC) is regulated by local Ca release (LCR) from the sarcoplasmic reticulum via Ca release channels (ryanodine receptors,...
2.
Winicki N, Nanavati A, Morrell C, Moen J, Axsom J, Krawczyk M, et al.
Front Cardiovasc Med
. 2023 Feb;
9:1096887.
PMID: 36741836
Background: Aging is associated with increased levels of reactive oxygen species and inflammation that disrupt proteostasis and mitochondrial function and leads to organism-wide frailty later in life. ARA290 (cibinetide), an...
3.
Tarasov K, Chakir K, Riordon D, Lyashkov A, Ahmet I, Perino M, et al.
Elife
. 2022 Dec;
11.
PMID: 36515265
Adult (3 month) mice with cardiac-specific overexpression of adenylyl cyclase (AC) type VIII (TG) adapt to an increased cAMP-induced cardiac workload (~30% increases in heart rate, ejection fraction and cardiac...
4.
Bychkov R, Juhaszova M, Calvo-Rubio Barrera M, Donald L, Coletta C, Shumaker C, et al.
JACC Clin Electrophysiol
. 2022 Oct;
8(10):1191-1215.
PMID: 36182566
Background: The sinoatrial node (SAN) of the heart produces rhythmic action potentials, generated via calcium signaling within and among pacemaker cells. Our previous work has described the SAN as composed...
5.
Juhaszova M, Kobrinsky E, Zorov D, Aon M, Cortassa S, Sollott S
Function (Oxf)
. 2022 May;
3(3):zqac018.
PMID: 35601666
No abstract available.
6.
Juhaszova M, Kobrinsky E, Zorov D, Nuss H, Yaniv Y, Fishbein K, et al.
Function (Oxf)
. 2022 Mar;
3(2):zqab065.
PMID: 35229078
ATP synthase (FF) synthesizes daily our body's weight in ATP, whose production-rate can be transiently increased several-fold to meet changes in energy utilization. Using purified mammalian FF-reconstituted proteoliposomes and isolated...
7.
Mancardi D, Pagliaro P, Ridnour L, Tocchetti C, Miranda K, Juhaszova M, et al.
Antioxidants (Basel)
. 2022 Feb;
11(2).
PMID: 35204265
Donors of nitroxyl (HNO), the one electron-reduction product of nitric oxide (NO), positively modulate cardiac contractility/relaxation while limiting ischemia-reperfusion (I/R) injury. The mechanisms underpinning HNO anti-ischemic effects remain poorly understood....
8.
Juhaszova M, Kobrinsky E, Zorov D, Nuss H, Yaniv Y, Fishbein K, et al.
Function (Oxf)
. 2022 Feb;
3(2):zqac001.
PMID: 35187492
We demonstrated that ATP synthase serves the of a primary mitochondrial K "uniporter," i.e., the primary way for K to enter mitochondria. This K entry is proportional to ATP synthesis,...
9.
Cortassa S, Aon M, Juhaszova M, Kobrinsky E, Zorov D, Sollott S
J Mol Cell Cardiol
. 2021 Dec;
165:9-18.
PMID: 34954465
ATP synthase (FF) is a rotary molecular engine that harnesses energy from electrochemical-gradients across the inner mitochondrial membrane for ATP synthesis. Despite the accepted tenet that FF transports exclusively H,...
10.
Aon M, Cortassa S, Juhaszova M, Gonzalez-Reyes J, Calvo-Rubio M, Villalba J, et al.
NPJ Aging Mech Dis
. 2021 Jan;
7(1):1.
PMID: 33398019
The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity. Maximal respiratory rate capacity, a metabolic performance measure, is one of the best...