Mads Gyrd-Hansen
Overview
Explore the profile of Mads Gyrd-Hansen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
43
Citations
2920
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Vind A, Wu Z, Firdaus M, Snieckute G, Toh G, Jessen M, et al.
Mol Cell
. 2024 Nov;
84(24):4774-4789.e9.
PMID: 39591967
Solar UVB light causes damage to the outermost layer of skin. This insult induces rapid local responses, such as dermal inflammation, keratinocyte cell death, and epidermal thickening, all of which...
2.
Gyrd-Hansen M, Kajaste-Rudnitski A, Manel N, Rehwinkel J, van der Veen A, Iannacone M
Nat Immunol
. 2024 Jul;
25(8):1322-1325.
PMID: 39009840
No abstract available.
3.
Mannion J, Gifford V, Bellenie B, Fernando W, Garcia L, Wilson R, et al.
Immunity
. 2024 May;
57(7):1514-1532.e15.
PMID: 38788712
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions as a critical stress sentinel that coordinates cell survival, inflammation, and immunogenic cell death (ICD). Although the catalytic function of RIPK1 is required to...
4.
Vringer E, Heilig R, Riley J, Black A, Cloix C, Skalka G, et al.
EMBO J
. 2024 Feb;
43(6):904-930.
PMID: 38337057
Mitochondrial outer membrane permeabilisation (MOMP) is often essential for apoptosis, by enabling cytochrome c release that leads to caspase activation and rapid cell death. Recently, MOMP has been shown to...
5.
Peng R, Wang C, Wang-Kan X, Idorn M, Kjaer M, Zhou F, et al.
EMBO Rep
. 2022 Oct;
23(12):e55839.
PMID: 36268590
ZBP1 is an interferon-induced cytosolic nucleic acid sensor that facilitates antiviral responses via RIPK3. Although ZBP1-mediated programmed cell death is widely described, whether and how it promotes inflammatory signaling is...
6.
Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
Elliott P, Leske D, Wagstaff J, Schlicher L, Berridge G, Maslen S, et al.
Cell Rep
. 2021 Oct;
37(1):109777.
PMID: 34610306
Non-degradative ubiquitin chains and phosphorylation events govern signaling responses by innate immune receptors. The deubiquitinase CYLD in complex with SPATA2 is recruited to receptor signaling complexes by the ubiquitin ligase...
7.
Klaessens S, Stroobant V, Hoffmann D, Gyrd-Hansen M, Pilotte L, Vigneron N, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(23).
PMID: 34074763
Maintaining stable tryptophan levels is required to control neuronal and immune activity. We report that tryptophan homeostasis is largely controlled by the stability of tryptophan 2,3-dioxygenase (TDO), the hepatic enzyme...
8.
Nikhar S, Siokas I, Schlicher L, Lee S, Gyrd-Hansen M, Degterev A, et al.
Eur J Med Chem
. 2021 Feb;
215:113252.
PMID: 33601309
Receptor interacting protein kinase-2 (RIPK2) is an enzyme involved in the transduction of pro-inflammatory nucleotide-binding oligomerization domain (NOD) cell signaling, a pathway implicated in numerous chronic inflammatory conditions. Herein, a...
9.
Fiil B, Gyrd-Hansen M
Cell Death Differ
. 2021 Jan;
28(2):557-569.
PMID: 33473179
Ubiquitination is an essential post-translational modification that regulates most cellular processes. The assembly of ubiquitin into polymeric chains by E3 ubiquitin ligases underlies the pleiotropic functions ubiquitin chains regulate. Ubiquitin...
10.
Topal Y, Gyrd-Hansen M
Semin Cell Dev Biol
. 2020 Jul;
109:144-150.
PMID: 32631784
The receptor-interacting protein kinases (RIPKs) are key regulators of inflammatory signalling and cell death pathways triggered by innate immune receptors, and RIPKs have emerged as promising therapeutic targets for treatment...