Mads E Hauberg
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Explore the profile of Mads E Hauberg including associated specialties, affiliations and a list of published articles.
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19
Citations
1130
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Recent Articles
1.
Fulton S, Bendl J, Gameiro-Ros I, Fullard J, Al-Kachak A, Lepack A, et al.
bioRxiv
. 2023 May;
PMID: 37205394
Hyperexcitability in the orbitofrontal cortex (OFC) is a key clinical feature of anhedonic domains of Major Depressive Disorder (MDD). However, the cellular and molecular substrates underlying this dysfunction remain unknown....
2.
Bendl J, Hauberg M, Girdhar K, Im E, Vicari J, Rahman S, et al.
Nat Neurosci
. 2022 Sep;
25(10):1366-1378.
PMID: 36171428
To characterize the dysregulation of chromatin accessibility in Alzheimer's disease (AD), we generated 636 ATAC-seq libraries from neuronal and nonneuronal nuclei isolated from the superior temporal gyrus and entorhinal cortex...
3.
Zhao B, Li T, Smith S, Xiong D, Wang X, Yang Y, et al.
Nat Genet
. 2022 Apr;
54(4):508-517.
PMID: 35393594
The human brain forms functional networks of correlated activity, which have been linked with both cognitive and clinical outcomes. However, the genetic variants affecting brain function are largely unknown. Here,...
4.
Girdhar K, Hoffman G, Bendl J, Rahman S, Dong P, Liao W, et al.
Nat Neurosci
. 2022 Mar;
25(4):474-483.
PMID: 35332326
Chromosomal organization, scaling from the 147-base pair (bp) nucleosome to megabase-ranging domains encompassing multiple transcriptional units, including heritability loci for psychiatric traits, remains largely unexplored in the human brain. In...
5.
McKenzie A, Wang M, Hauberg M, Fullard J, Kozlenkov A, Keenan A, et al.
Sci Rep
. 2021 Sep;
11(1):19430.
PMID: 34561470
No abstract available.
6.
Zhao B, Li T, Yang Y, Wang X, Luo T, Shan Y, et al.
Science
. 2021 Jun;
372(6548).
PMID: 34140357
Brain regions communicate with each other through tracts of myelinated axons, commonly referred to as white matter. We identified common genetic variants influencing white matter microstructure using diffusion magnetic resonance...
7.
Hauberg M, Creus-Muncunill J, Bendl J, Kozlenkov A, Zeng B, Corwin C, et al.
Nat Commun
. 2020 Nov;
11(1):5581.
PMID: 33149216
The chromatin landscape of human brain cells encompasses key information to understanding brain function. Here we use ATAC-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic...
8.
Egervari G, Akpoyibo D, Rahman T, Fullard J, Callens J, Landry J, et al.
Nat Commun
. 2020 Sep;
11(1):4634.
PMID: 32929078
The current opioid epidemic necessitates a better understanding of human addiction neurobiology to develop efficacious treatment approaches. Here, we perform genome-wide assessment of chromatin accessibility of the human striatum in...
9.
Hoffman G, Bendl J, Voloudakis G, Montgomery K, Sloofman L, Wang Y, et al.
Sci Data
. 2019 Sep;
6(1):180.
PMID: 31551426
Schizophrenia and bipolar disorder are serious mental illnesses that affect more than 2% of adults. While large-scale genetics studies have identified genomic regions associated with disease risk, less is known...
10.
Wang M, Beckmann N, Roussos P, Wang E, Zhou X, Wang Q, et al.
Sci Data
. 2018 Sep;
5:180185.
PMID: 30204156
Alzheimer's disease (AD) affects half the US population over the age of 85 and is universally fatal following an average course of 10 years of progressive cognitive disability. Genetic and...