Maddalena Pacelli
Overview
Explore the profile of Maddalena Pacelli including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
7
Followers
0
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Recent Articles
1.
Rosignoli S, Giordani S, Pacelli M, Guarguaglini G, Paiardini A
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001507
PROteolysis TArgeting Chimeras (PROTACs) offer a therapeutic modality for protein target engagement, exploiting the ubiquitin-proteasome system to achieve precise degradation of a protein of interest. Recent advancements in understanding the...
2.
Pitaro M, Antonini G, Arcovito A, Buccisano F, De Lauro A, Irno Consalvo M, et al.
Front Immunol
. 2025 Jan;
15:1520103.
PMID: 39742266
Background: Mature T-cell neoplasms arise from the neoplastic transformation of a single T lymphocyte, and all cells in a neoplastic clone share the same V segment in the beta chain...
3.
Rosignoli S, Pacelli M, Manganiello F, Paiardini A
FEBS Open Bio
. 2024 Sep;
15(2):202-222.
PMID: 39313455
AlphaFold and similar groundbreaking, AI-based tools, have revolutionized the field of structural bioinformatics, with their remarkable accuracy in ab-initio protein structure prediction. This success has catalyzed the development of new...
4.
Alles J, Legnini I, Pacelli M, Rajewsky N
iScience
. 2023 Jan;
26(1):105878.
PMID: 36691625
Poly(A) tails protect RNAs from degradation and their deadenylation rates determine RNA stability. Although poly(A) tails are generated in the nucleus, deadenylation of tails has mostly been investigated within the...