Madalee G Wulf
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Explore the profile of Madalee G Wulf including associated specialties, affiliations and a list of published articles.
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6
Citations
89
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Recent Articles
1.
Havel V, Kruegel A, Bechand B, McIntosh S, Stallings L, Hodges A, et al.
Nat Commun
. 2024 Sep;
15(1):8118.
PMID: 39304653
Ibogaine and its main metabolite noribogaine provide important molecular prototypes for markedly different treatment of substance use disorders and co-morbid mental health illnesses. However, these compounds present a cardiac safety...
2.
Ugolini C, Mulroney L, Leger A, Castelli M, Criscuolo E, Kavanagh Williamson M, et al.
Nucleic Acids Res
. 2022 Mar;
50(6):3475-3489.
PMID: 35244721
The SARS-CoV-2 virus has a complex transcriptome characterised by multiple, nested subgenomic RNAsused to express structural and accessory proteins. Long-read sequencing technologies such as nanopore direct RNA sequencing can recover...
3.
Mulroney L, Wulf M, Schildkraut I, Tzertzinis G, Buswell J, Jain M, et al.
RNA
. 2021 Nov;
28(2):162-176.
PMID: 34728536
Nanopore sequencing devices read individual RNA strands directly. This facilitates identification of exon linkages and nucleotide modifications; however, using conventional direct RNA nanopore sequencing, the 5' and 3' ends of...
4.
Wulf M, Maguire S, Dai N, Blondel A, Posfai D, Krishnan K, et al.
Nucleic Acids Res
. 2021 Sep;
50(1):e2.
PMID: 34581823
Template-switching reverse transcription is widely used in RNA sequencing for low-input and low-quality samples, including RNA from single cells or formalin-fixed paraffin-embedded (FFPE) tissues. Previously, we identified the native eukaryotic...
5.
Wulf M, Maguire S, Humbert P, Dai N, Bei Y, Nichols N, et al.
J Biol Chem
. 2019 Oct;
294(48):18220-18231.
PMID: 31640989
Single-cell RNA-Seq (scRNA-Seq) has led to an unprecedented understanding of gene expression and regulation in individual cells. Many scRNA-Seq approaches rely upon the template switching property of Moloney murine leukemia...
6.
Wulf M, Buswell J, Chan S, Dai N, Marks K, Martin E, et al.
Sci Rep
. 2019 Jun;
9(1):8594.
PMID: 31197197
Eukaryotic mRNAs are modified at their 5' end early during transcription by the addition of N7-methylguanosine (mG), which forms the "cap" on the first 5' nucleotide. Identification of the 5'...