Mackenzie M Shipley
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Explore the profile of Mackenzie M Shipley including associated specialties, affiliations and a list of published articles.
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13
Citations
379
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Recent Articles
1.
Rathbun M, Shipley M, Bowen C, Selke S, Wald A, Johnston C, et al.
PLoS Pathog
. 2022 May;
18(5):e1010437.
PMID: 35587470
Herpes simplex virus (HSV) causes chronic infection in the human host, characterized by self-limited episodes of mucosal shedding and lesional disease, with latent infection of neuronal ganglia. The epidemiology of...
2.
Mehta S, Szpara M, Rooney B, Diak D, Shipley M, Renner D, et al.
Viruses
. 2022 Apr;
14(4).
PMID: 35458519
Human alpha herpesviruses herpes simplex virus (HSV-1) and varicella zoster virus (VZV) establish latency in various cranial nerve ganglia and often reactivate in response to stress-associated immune system dysregulation. Reactivation...
3.
Shipley M, Prasad V, Doepker L, Dingens A, Ralph D, Harkins E, et al.
Elife
. 2021 Jul;
10.
PMID: 34263727
Stimulating broadly neutralizing antibodies (bnAbs) directly from germline remains a barrier for HIV vaccines. HIV superinfection elicits bnAbs more frequently than single infection, providing clues of how to elicit such...
4.
Simonich C, Shipley M, Doepker L, Gobillot T, Garrett M, Cale E, et al.
Cell Rep Med
. 2021 Jul;
2(6):100314.
PMID: 34195680
Increasing evidence suggests infants develop unique neutralizing antibody (nAb) responses to HIV compared to adults. Here, we dissected the nAb response of an infant whose virus is in clinical trials...
5.
Stoddard C, Galloway J, Chu H, Shipley M, Sung K, Itell H, et al.
Cell Rep
. 2021 May;
35(8):109164.
PMID: 33991511
A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope targets of the SARS-CoV-2 antibody...
6.
Doepker L, Simonich C, Ralph D, Shipley M, Garrett M, Gobillot T, et al.
J Virol
. 2020 Feb;
94(9).
PMID: 32075936
Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do not become infected. There is...
7.
Shipley M, Rathbun M, Szpara M
Methods Mol Biol
. 2019 Oct;
2060:199-217.
PMID: 31617180
To date more than 400 genomes of herpes simplex virus 1 (HSV-1) and the distantly related HSV-2 have been examined using deep sequencing techniques. This powerful approach has been especially...
8.
Shipley M, Renner D, Pandey U, Ford B, Bloom D, Grose C, et al.
Cold Spring Harb Mol Case Stud
. 2019 Oct;
5(6).
PMID: 31582464
Here we present a personalized viral genomics approach to investigating a rare case of perinatal herpes simplex virus 1 (HSV-1) transmission that ended in death of both mother and neonate....
9.
Shipley M, Renner D, Ott M, Bloom D, Koelle D, Johnston C, et al.
J Infect Dis
. 2018 Jun;
218(4):595-605.
PMID: 29920588
Here we present genomic and in vitro analyses of temporally separated episodes of herpes simplex virus type 1 (HSV-1) shedding by an HSV-1-seropositive and human immunodeficiency virus (HIV)/HSV-2-seronegative individual who...
10.
Shipley M, Mangold C, Kuny C, Szpara M
J Virol
. 2017 Sep;
91(23).
PMID: 28956768
Neuron-virus interactions that occur during herpes simplex virus (HSV) infection are not fully understood. Neurons are the site of lifelong latency and are a crucial target for long-term suppressive therapy...