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Maciej Wiktor

Explore the profile of Maciej Wiktor including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 166
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Recent Articles
1.
Maszczak-Seneczko D, Wiktor M, Skurska E, Wiertelak W, Olczak M
Int J Mol Sci . 2022 Aug; 23(15). PMID: 35955785
Nucleotide sugars (NSs) serve as substrates for glycosylation reactions. The majority of these compounds are synthesized in the cytoplasm, whereas glycosylation occurs in the endoplasmic reticulum (ER) and Golgi lumens,...
2.
Kot M, Mazurkiewicz E, Wiktor M, Wiertelak W, Mazur A, Rahalevich A, et al.
Cells . 2022 Jul; 11(15). PMID: 35892570
In mammalian cells, SLC35A2 delivers UDP-galactose for galactosylation reactions that take place predominantly in the Golgi lumen. Mutations in the corresponding gene cause a subtype of a congenital disorder of...
3.
Skurska E, Szulc B, Maszczak-Seneczko D, Wiktor M, Wiertelak W, Makowiecka A, et al.
J Biol Chem . 2022 Jun; 298(8):102206. PMID: 35772493
Mutations in the SLC35C1 gene encoding the Golgi GDP-fucose transporter are known to cause leukocyte adhesion deficiency II. However, improvement of fucosylation in leukocyte adhesion deficiency II patients treated with...
4.
Wiktor M, Wiertelak W, Maszczak-Seneczko D, Balwierz P, Szulc B, Olczak M
J Proteomics . 2021 Jul; 249:104321. PMID: 34242836
Nucleotide sugar transporters (NSTs) are ER and Golgi-resident members of the solute carrier 35 (SLC35) family which supply substrates for glycosylation by exchanging lumenal nucleotide monophosphates for cytosolic nucleotide sugars....
5.
Bazan B, Wiktor M, Maszczak-Seneczko D, Olczak T, Kaczmarek B, Olczak M
PLoS One . 2018 Nov; 13(11):e0207521. PMID: 30458018
SLC35B4 belongs to the solute carrier 35 (SLC35) family whose best-characterized members display a nucleotide sugar transporting activity. Using an experimental model of HepG2 cells and indirect immunofluorescent staining, we...
6.
Wiktor M, Weichert D, Howe N, Huang C, Olieric V, Boland C, et al.
Nat Commun . 2017 Jul; 8:15952. PMID: 28675161
Lipoproteins serve essential roles in the bacterial cell envelope. The posttranslational modification pathway leading to lipoprotein synthesis involves three enzymes. All are potential targets for the development of new antibiotics....
7.
Wiktor M, Hartley O, Grzesiek S
Biophys J . 2013 Dec; 105(11):2586-97. PMID: 24314089
RANTES (CCL5) is a chemokine that recruits immune cells to inflammatory sites by interacting with the G-protein coupled receptor CCR5, which is also the primary coreceptor used together with CD4...
8.
Vajpai N, Nisius L, Wiktor M, Grzesiek S
Proc Natl Acad Sci U S A . 2013 Jan; 110(5):E368-76. PMID: 23284170
Proteins denature not only at high, but also at low temperature as well as high pressure. These denatured states are not easily accessible for experiment, because usually heat denaturation causes...
9.
Wiktor M, Morin S, Sass H, Kebbel F, Grzesiek S
J Biomol NMR . 2012 Dec; 55(1):79-95. PMID: 23229639
The chemokine receptor CCR5 belongs to the class of G protein-coupled receptors. Besides its role in leukocyte trafficking, it is also the major HIV-1 coreceptor and hence a target for...
10.
Makowski M, Lisowski M, Maciag A, Wiktor M, Szlachcic A, Lis T
Acta Crystallogr C . 2010 Mar; 66(Pt 3):o119-23. PMID: 20203407
Comparison of the crystal structures of two pentadehydropeptides containing DeltaPhe residues, namely (Z,Z)-N-(tert-butoxycarbonyl)glycyl-alpha,beta-phenylalanylglycyl-alpha,beta-phenylalanylglycine (or Boc(0)-Gly(1)-Delta(Z)Phe(2)-Gly(3)-Delta(Z)Phe(4)-Gly(5)-OH) methanol solvate, C(29)H(33)N(5)O(8) x CH(4)O, (I), and (E,E)-N-(tert-butoxycarbonyl)glycyl-alpha,beta-phenylalanylglycyl-alpha,beta-phenylalanylglycine (or Boc(0)-Gly(1)-Delta(E)Phe(2)-Gly(3)-Delta(E)Phe(4)-Gly(5)-OH), C(29)H(33)N(5)O(8), (II), indicates that the...