Alpha 2.0
Login Register
» Authors » Macarena Ortiz

Macarena Ortiz

Explore the profile of Macarena Ortiz including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 19
Citations 417
Followers 0
Related Specialties
Biochemistry
Chemistry
Endocrinology
Top 10 Co-Authors
Rodrigo Valenzuela
Francisca Echeverria
Luis A Videla
Alejandra Espinosa
Daniela Alvarez
Paola Illesca
Manuel Maliqueo
Maria Catalina Hernandez-Rodas
Nicolas Crisosto
Miguel Angel Rincon-Cervera
Published In
Food Funct
Prostaglandins Leukot Essent Fatty Acids
Curr Med Chem
Nutrients
Transfus Apher Sci
Affiliations
Soon will be listed here.
Recent Articles
1.
Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice
Alvarez D, Ortiz M, Valdebenito G, Crisosto N, Echiburu B, Valenzuela R, et al.
Nutrients . 2023 Nov; 15(21). PMID: 37960348
A high-fat diet (HFD) during pregnancy promotes fat accumulation and reduces docosahexaenoic acid (DHA) levels in the liver of the offspring at postnatal ages, which can depend on fetal sex....
2.
Linoleic and Arachidonic Fatty Acids and their Potential Relationship with Inflammation, Pregnancy, and Fetal Development
Ortiz M, Alvarez D, Munoz Y, Crisosto N, Valenzuela R, Maliqueo M
Curr Med Chem . 2023 Jul; 31(31):5046-5060. PMID: 37415369
Objective: To summarize the evidence of maternal, placental, and fetal alterations that an excessive intake of n-6 polyunsaturated FAs (PUFAs), LA, and AA, could produce during pregnancy. Methods: A thorough...
3.
Association between maternal obesity, essential fatty acids and biomarkers of fetal liver function
Ortiz M, Sanchez F, Alvarez D, Flores C, Salas-Perez F, Valenzuela R, et al.
Prostaglandins Leukot Essent Fatty Acids . 2023 Feb; 190:102541. PMID: 36736061
Maternal obesity and the imbalance in linoleic acid (C18:2 n-6, LA) and alpha-linolenic acid (C18:3 n-3, ALA) levels are related with hepatic disturbances in the offspring. However, whether these alterations...
4.
Rodent models in placental research. Implications for fetal origins of adult disease
Aguilera N, Salas-Perez F, Ortiz M, Alvarez D, Echiburu B, Maliqueo M
Anim Reprod . 2022 May; 19(1):e20210134. PMID: 35493783
Rodent models in rats, mice, and guinea pigs have been extremely helpful to gain insight into pregnancy physiology and pathologies-related. Moreover, they have allowed understanding the mechanism that links an...
5.
Real-World Characteristics and Outcome of Patients Treated With Single-Agent Ibrutinib for Chronic Lymphocytic Leukemia in Spain (IBRORS-LLC Study)
Abrisqueta P, Loscertales J, Terol M, Ramirez Payer A, Ortiz M, Perez I, et al.
Clin Lymphoma Myeloma Leuk . 2021 Sep; 21(12):e985-e999. PMID: 34511320
Background: Ibrutinib demonstrated remarkable efficacy and favorable tolerability in patients with untreated or relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL), including those with high-risk genetic alterations. The IBRORS-CLL study assessed the...
6.
Impact of Maternal Obesity on the Metabolism and Bioavailability of Polyunsaturated Fatty Acids during Pregnancy and Breastfeeding
Alvarez D, Munoz Y, Ortiz M, Maliqueo M, Chouinard-Watkins R, Valenzuela R
Nutrients . 2020 Dec; 13(1). PMID: 33374585
: Prenatal and postnatal development are closely related to healthy maternal conditions that allow for the provision of all nutritional requirements to the offspring. In this regard, an appropriate supply...
7.
The metabolic dysfunction of white adipose tissue induced in mice by a high-fat diet is abrogated by co-administration of docosahexaenoic acid and hydroxytyrosol
Illesca P, Valenzuela R, Espinosa A, Echeverria F, Soto-Alarcon S, Ortiz M, et al.
Food Funct . 2020 Oct; 11(10):9086-9102. PMID: 33026007
Background: Nutritional interventions are promising tools for the prevention of obesity. The n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) docosahexaenoic acid (DHA) modulates immune and metabolic responses while the antioxidant...
8.
Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration
Ortiz M, Soto-Alarcon S, Orellana P, Espinosa A, Campos C, Lopez-Arana S, et al.
Dig Liver Dis . 2020 Jul; 52(8):895-904. PMID: 32620521
Objective: Obesity-induced by high-fat diet (HFD) is associated with liver steatosis, oxidative stress and mitochondrial dysfunction, which can be eluded by the co-administration of the lipid metabolism modulator docosahexaenoic acid...
9.
High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration
Echeverria F, Valenzuela R, Bustamante A, Alvarez D, Ortiz M, Espinosa A, et al.
Food Funct . 2019 Sep; 10(9):6170-6183. PMID: 31501836
High-fat-diet (HFD) feeding is associated with liver oxidative stress (OS), n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) depletion, hepatic steatosis and mitochondrial dysfunction. Our hypothesis is that the HFD-induced liver...
10.
Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach
Soto-Alarcon S, Ortiz M, Orellana P, Echeverria F, Bustamante A, Espinosa A, et al.
Biofactors . 2019 Aug; 45(6):930-943. PMID: 31454114
Attenuation of high-fat diet (HFD)-induced liver steatosis is accomplished by different nutritional interventions. Considering that the n-3 PUFA docosahexaenoic acid (DHA) modulates lipid metabolism and the antioxidant hydroxytyrosol (HT) diminishes...