Maartje van den Biggelaar
Overview
Explore the profile of Maartje van den Biggelaar including associated specialties, affiliations and a list of published articles.
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75
Citations
977
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Recent Articles
1.
Smit E, Munoz Sandoval D, Kreft I, van der Meer P, van der Zwaan C, Voorberg J, et al.
Transl Med Commun
. 2025 Mar;
9(1):27.
PMID: 40078206
Background: Bone marrow aplasia is a common feature in acute myeloid leukemia (AML) patients during their remission induction treatment, and is associated with potential complications such as bleeding, infection and...
2.
Monard A, Mussert C, van Duijl T, Kruip M, Henskens Y, van den Biggelaar M, et al.
Res Pract Thromb Haemost
. 2024 Dec;
8(8):102625.
PMID: 39687924
In more than half of the individuals with a clinically relevant bleeding tendency who are referred to hemostasis experts, no biological etiology can be found after extensive laboratory testing. These...
3.
Miranda M, Hansen B, Wehbi B, Porcheddu V, van Alphen F, Kaijen P, et al.
Haematologica
. 2024 Dec;
PMID: 39665218
The development of neutralizing antibodies (inhibitors) against coagulation factor VIII (FVIII) poses a major challenge in hemophilia A (HA) treatment. The formation of FVIII inhibitors is a CD4+ T-cell dependent...
4.
Verkerk T, de Waard A, Koomen S, Sanders J, Jorritsma T, Pappot A, et al.
Eur J Immunol
. 2024 Dec;
55(2):e202451129.
PMID: 39655358
The development of an effective antitumor response relies on the synergistic actions of various immune cells that recognize tumor cells via distinct receptors. Tumors, however, often manipulate receptor-ligand interactions to...
5.
Miranda M, Brandsma E, Robben L, Van Dender H, van Alphen F, Fijnvandraat K, et al.
J Thromb Haemost
. 2024 Dec;
23(3):836-848.
PMID: 39617188
Background: The main complication in hemophilia A treatment is the development of inhibitory antibodies against factor (F)VIII. Immune tolerance induction, the gold standard for eradicating anti-FVIII antibodies, is efficient in...
6.
Michels E, Chouchane O, de Brabander J, de Vos A, Faber D, Douma R, et al.
Front Immunol
. 2024 Nov;
15:1470383.
PMID: 39493755
Introduction: Neutrophils play a dichotomous role in community-acquired pneumonia (CAP), providing protection and potentially causing damage. Existing research on neutrophil function in CAP relies on animal studies, leaving a gap...
7.
Monard A, Castoldi E, de Simone I, Wichapong K, van Duijl T, van den Biggelaar M, et al.
Front Cardiovasc Med
. 2024 Oct;
11:1488602.
PMID: 39473893
Introduction: Hypodysfibrinogenemia is a rare congenital fibrinogen disorder (CFD) which may induce thrombotic and bleeding events. Therefore, patient management needs careful evaluation. Routine coagulation tests are inadequate to predict the...
8.
Groten S, van den Eshof B, van Alphen F, Meijer A, van den Biggelaar M, Hoogendijk A
J Thromb Haemost
. 2024 Oct;
23(2):717-730.
PMID: 39442624
Background: The vascular endothelial cell (EC) monolayer plays a crucial part in maintaining hemostasis. An extensive array of G protein-coupled receptors allows ECs to dynamically act on key hemostatic stimuli...
9.
Kreft I, van de Geer A, Smit E, van der Zwaan C, van Alphen F, Meijer A, et al.
Cancer Rep (Hoboken)
. 2024 Oct;
7(10):e70024.
PMID: 39441646
Background: Acute myeloid leukemia (AML) is a heterogenous and complex blood cancer requiring aggressive treatment. Early identification and prediction of the complications following treatment is vital for effective disease management....
10.
Smit E, Romijn M, Langerhorst P, van der Zwaan C, van der Staaij H, Rotteveel J, et al.
Pediatr Res
. 2024 Aug;
PMID: 39152333
Background: Preterm infants, especially those born small for gestational age (SGA), are at risk of short-term and long-term health complications. Characterization of changes in circulating proteins postnatally in preterm infants...