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M Z Kounnas

Explore the profile of M Z Kounnas including associated specialties, affiliations and a list of published articles. Areas
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Citations 800
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Recent Articles
1.
Strickland D, Kounnas M
Trends Cardiovasc Med . 2011 Jan; 7(1):9-16. PMID: 21235858
Serine proteinase inhibitors (serpins) such as antithrombin III inhibit target proteinases by forming a stable complexwith the enzyme. Once formed, several serpin-enzyme complexes (SECs) are removed from the circulation by...
2.
Kang D, Pietrzik C, Baum L, Chevallier N, Merriam D, Kounnas M, et al.
J Clin Invest . 2000 Nov; 106(9):1159-66. PMID: 11067868
Susceptibility to Alzheimer's disease (AD) is governed by multiple genetic factors. Remarkably, the LDL receptor-related protein (LRP) and its ligands, apoE and alpha2M, are all genetically associated with AD. In...
3.
Higazi A, Upson R, Cohen R, Manuppello J, Bognacki J, Henkin J, et al.
Blood . 1996 Jul; 88(2):542-51. PMID: 8695802
Binding of urokinase-type plasminogen activator (uPA) to its glycosylphosphatidylinositol-anchored receptor (uPAR) initiates signal transduction, adhesion, and migration in certain cell types. To determine whether some of these activities may be...
4.
Kounnas M, Church F, Argraves W, Strickland D
J Biol Chem . 1996 Mar; 271(11):6523-9. PMID: 8626456
The inhibition of proteinase activity by members of the serine proteinase inhibitor (serpin) family is a critical regulatory mechanism for a variety of biological processes. Once formed, the serpin enzyme...
5.
Kounnas M, Moir R, Rebeck G, Bush A, Argraves W, Tanzi R, et al.
Cell . 1995 Jul; 82(2):331-40. PMID: 7543026
The secreted form of beta-amyloid precursor protein (APP) containing the Kunitz proteinase inhibitor (KPI) domain, also called protease nexin II, is internalized and degraded by cells. We show that the...
6.
Strickland D, Kounnas M, Argraves W
FASEB J . 1995 Jul; 9(10):890-8. PMID: 7615159
The accumulation of excessive cholesterol-rich lipoproteins within vascular cells, the proliferation of vascular cells, and fibrin deposition are hallmark features of atherosclerosis. Evidence accumulated over the past few years supports...
7.
Kounnas M, Loukinova E, Stefansson S, Harmony J, Brewer B, Strickland D, et al.
J Biol Chem . 1995 Jun; 270(22):13070-5. PMID: 7768901
Glycoprotein 330 (gp330) is a member of a family of endocytic receptors related to the low density lipoprotein receptor. gp330 has previously been shown to bind a number of ligands...
8.
Stefansson S, Kounnas M, Henkin J, Mallampalli R, Chappell D, Strickland D, et al.
J Cell Sci . 1995 Jun; 108 ( Pt 6):2361-8. PMID: 7673355
Glycoprotein 330 (gp330) is a member of a family of receptors related to the low density lipoprotein receptor (LDLR). Although several ligands have been shown to bind gp330 in solid-phase...
9.
Mikhailenko I, Kounnas M, Strickland D
J Biol Chem . 1995 Apr; 270(16):9543-9. PMID: 7721883
Thrombospondin (TSP) is a cell and matrix glycoprotein that interacts with a variety of molecules. Newly synthesized thrombospondin is either incorporated into the extracellular matrix, or binds to the cell...
10.
Kounnas M, Chappell D, Wong H, Argraves W, Strickland D
J Biol Chem . 1995 Apr; 270(16):9307-12. PMID: 7721852
Hepatic lipase (HL) and lipoprotein lipase (LpL) are structurally related lipolytic enzymes that have distinct functions in lipoprotein catabolism. In addition to its lipolytic activity, LpL binds to very low...